by Differin  
$132.93 - 45 gram
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Differin contains the retinoid adapalene as its active ingredient. It is available in cream, lotion, or gel forms at a strength of 0.1%. A 0.3% strength is available in cream or gel form. Which strength and texture to choose is best determined by consulting your dermatologist and taking your personal preferences into account. As an example of costs, a 45-gram tube of Differin cream costs $132.93; the same size of alcohol-free gel costs $117.28. It is owned by Galderma, the company behind the Cetaphil brand. Adapalene can be used at the same time as benzoyl peroxide, which is something that cannot be said for tretinoin (the active ingredient in all forms of Retin-A). For more information about the active ingredient in Differin, please click on Retinoids from the Master Brand List.

Differin Lotion Contains Carbomer 941, Disodium Edetate, Medium Chain Triglycerides, Methylparaben, Phenoxyethanol, Poloxamer 124, Polyoxyl-6polyoxyl-32 Palmitostearate, PPG-12 / SMDI Copolymer, Propylene Glycol, Propylparaben, Sodium Hydroxide, Stearyl Alcohol, Purified Water.

Differin Gel Contains Adapalene 0.1% or 0.3% in a vehicle consisting of Carbomer 940, Edetate Disodium, Methylparaben, Poloxamer 182, Propylene Glycol, Purified Water, Sodium Hydroxide. May contain Hydrochloric Acid to adjust pH.

Differin Cream Contains 0.1% Adapalene in a base of Carbomer 934P, PEG-20 Methyl Glucose Sesquistearate, Glycerol, Squalane, Methyl Hydroxybenzoate, Propyl Hydroxybenzoate, Disodium Edetate, Methyl Glucose Sesquistearate, Phenoxyethanol, Cyclomethicone, Sodium Hydroxide, Purified Water.


Member Comments

Summary of Member Comments

  1. How would you rate the results? (4 = Best)

    4 / 4 Best
  2. Was this product a good value? (4 = Best)

    4 / 4 Best
  3. Would you recommend this product? (4 = Best)

    4 / 4 Best
Page of 1
  1. Lil
    Reviewed on Sunday, July 14, 2013
    • Value
      4 / 4
    • Results
      4 / 4
    • Recommend
      4 / 4
    • I've been using this product for years and prescibed by my dermatologist. He said that of all the otc retinoid products, the prescription cream works best. I use it for anti aging purposes even though it was designed for acne. He said it would make my skin look younger and it does! I switched to the less expensive product of Adapalene, of which it is made. It's less expensive, but you still need a prescription. I get compliments on my skin and I'm 68. Insurance won't cover this.

  2. Anonymous
    Reviewed on Saturday, December 01, 2012
    • Results
      4 / 4
    • Recommend
      4 / 4
    • Value
      4 / 4
    excellent for acne
    • I've been using the .01 gel for years for lifelong acne. I discovered that if I mix it with 2.5% benzoyl peroxide (I prefer Paula's Choice) the combination is the best topical I've ever used. I recommend you use it at night followed with a moisturizer. It's counter-intuitive, but I found that using a good moisturizer formulated for combination skin has actually further improved my acne in addition to controlling the dryness and flaking I used to be plagued with. The BP will tend to bleach sheets and clothing so I stick to ivory sheets and don't let it touch my regular clothing. Yes, the Differen is expensive but you only need a very small amount for each use and the tube will last a long time. It does need a prescription. During the day I use a BHA product covered with sunscreen or SPF make-up and this also helps. I like Neutrogena Oil Free Hydrating 3 in 1 Acne Stress Control (I find it on the internet) or one of the Paula's Choice products. It's taken years of experimenting but I finally found the regimen that works for me, maybe it will work for you.

About the Experts

Paula Begoun is the best-selling author of 20 books on skin care and makeup. She is known worldwide as the Cosmetics Cop and creator of Paula's Choice. Paula's expertise has led to hundreds of appearances on national and international television including:

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The Paula's Choice Research Team is dedicated to helping you find the absolute best products for your skin, using research-based criteria to review beauty products from an honest, balanced perspective. Each member of the team was personally trained by Paula herself.

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