This is made to sound like a specialized, targeted treatment product for women struggling with acne and its resulting discolorations, but ends up being a mixed bag of effective, questionable, and irritating ingredients. The effective portion is the 2% salicylic acid and the pH of 4, which allows this lightweight lotion to exfoliate and help dislodge blackheads.
The most intriguing ingredient in this product is spironolactone. It’s a synthetic antiandrogen drug that’s worth considering if you have acne, though it’s typically given orally and is considered controversial. Essentially, spironolactone works by blocking hormone formation (specifically, androgens, the male hormones that trigger acne) in the body. Research on topical use of spironolactone is building but so far hasn’t been knock-our-socks-off impressive. A double-blind study involving almost 80 female subjects showed that those applying 5% spironolactone (which is likely the amount this product contains) had a reduction in acne lesion count but not overall acne severity compared with women using a placebo (Source: The Journal of Dermatological Treatment, October 2010, Epublication).
A more recent compendium of studies reviewing acne treatments concluded that spironolactone “failed to show any benefit”, which is disappointing, but we know that acne can be stubborn and not everyone will have results from the various treatments available (Source: Clinical and Experimental Dermatology, March 2011, pages 119–123).
What earns this product its poor rating are the irritants it contains, including a form of resorcinol, arnica, and Spanish pellitory (Anacylus pyrethrum), and a strikingly high amount of fragrance, which isn’t the least bit anti-acne or anti-discoloration. All of these can make acne worse by stimulating nerve endings at the base of the pore to produce more oil, not to mention needless irritation prolongs skin’s healing time.
There are some intriguing, skin-beneficial ingredients in this BHA lotion, but the amounts are likely inconsequential for skin and the irritants plus the controversial nature of spironolactone make this a product to pass on.
Age Intervention Transitions is an extraordinary technology for stubborn female adult acne. Age Intervention Transitions combines acne clearing and prevention with remarkable skin resurfacing and brightening technology and antioxidants. The technologies in Transitions not only improve acne, but also reduce the appearance of discoloration associated with acne and post acne inflammation.
Active Ingredient: Salicylic Acid - 2.0% Inactive Ingredients: Water/Aqua/Eau, Butylene Glycol, Spironolactone, Glycerin, Hydroxypropyl Starch Phosphate, Fragrance (Parfum), Caprylic/Capric Triglyceride, Creatine, Hexylresorcinol, Myristoyl Tripeptide-4, Arnica Montana Flower Extract, Anacyclus Pyrethrum Root Extract, Camellia Oleifera Leaf Extract, Cucumis Sativus (Cucumber) Fruit Extract, Linseed Oil/Palm Oil Aminopropanediol Esters, Dipotassium Glycyrrhizate, Tocopheryl Acetate, Tocopherol, Mannan, Farnesol, Linalool, Linoleic Acid, Linolenic Acid, Xanthan Gum, Steareth-100, Steareth-2, Polysorbate 20, Hydroxyethylcellulose, Propylene Glycol, Triethanolamine, Diazolidinyl Urea, Propylparaben, Methylparaben.
Jan Marini Skin Research, Inc., was founded, of course, by Jan Marini, who originally started out marketing products for M.D. Formulations. Thus, it isn't surprising to find that her own line is also aimed at dermatologists, aestheticians, and plastic surgeons, much the way M.D. Formulations is. In direct contrast to many of the other skin-care lines in this niche market, Marini’s line stands out with its selection of far more realistic and varied skin-care products. First, there are no spiraling-out-of-control ingredient lists where everything is thrown in except the kitchen sink. Then, and more important, you will find some well-formulated products that include sunscreens, skin-lightening options, vitamin C products, and good glycolic acid–based alpha hydroxy acid (AHA) products, along with some outstanding retinol options.
It is interesting to observe that Marini attributes the research for her "topical form of lipid (fat) soluble Vitamin C that is stable and able to be absorbed" to the form "developed in conjunction with physician researcher Nicholas Perricone, M.D." Of course, Perricone has his own version of vitamin C products, which are quite similar to Marini's in that they also contain ascorbyl palmitate. That being the case, given that he claims his are the best ever with the highest concentration of the stuff, we wonder if she would now agree with his findings? At least compared to her former partners at M.D. Formulations, Marini's information about vitamin C is more accurately based (it's backed by published research) and there's only a minimal amount of hyperbole. In fact, when it comes to the information Marini and team present to the professionals who retail their products, this line wins high marks for its close-to-accurate information about how skin ages, what can be done to minimize and prevent future signs of aging, and the effects various products have on skin. Of course, you're supposed to believe her products have all the answers, but that's what the reviews below will elucidate.
For more information about Jan Marini Skin Research, Inc., call (888) 695-2611 or visit www.janmarini.com.