Cold Plasma Body was launched hot on the heels of Perricone’s Cold Plasma facial moisturizer and its eye cream counterpart. Now you can experience Perricone’s “revolutionary” Cold Plasma technology from head to toe, assuming you’re OK with spending hundreds of dollars for the questionable benefit it has for skin. As it turns out, this body moisturizer is more of a hardship than a privilege. Why? Though we rarely comment on a product’s specific scent—because odors are subjective and fragrance has nothing to do with the value of a brilliant formulation—it was agreed that we simply had to for this product. According to our experience, and the experience of numerous others who have posted reviews online, this product smells like a mixture of overripe shrimp and well-worn sweaty socks. We’re not exactly sure what’s contributing to the unpleasant aroma, but we did notice that it doesn’t fade.
As for the formula itself, it’s supposed to firm, plump, hydrate, and smooth your skin while reducing cellulite and giving your legs a toned, contoured appearance. Don’t hold your breath, or stop your aerobics class, because there is nothing in this product that will reduce cellulite or tone your legs. There is nothing unique to this formula that isn’t seen in dozens of other Perricone products that don’t make claims about cellulite or skin contouring.
This does contain an effective amount of glycolic acid, but the product’s pH of 9 means it has zero ability to exfoliate your skin (and a product with a pH of 9 is alkaline and potentially drying all on its own).
What about the DMAE (dimethyl MEA) that is so prominent on the ingredient list? DMAE is controversial because research has shown conflicting results. It seems to offer an initial benefit that improves skin, but these results are short-lived and eventually give way to destruction of the substances in skin that help build healthy collagen (Sources: Aesthetic Plastic Surgery, November-December 2007, pages 711–718; and American Journal of Clinical Dermatology, volume 6, 2005, pages 39–47).
Interestingly, there is a formulation challenge when using DMAE in skin-care products. For DMAE to maintain efficacy and stability, the product’s pH must be at least 10, which is highly alkaline and not good news for your skin. In fact, such a high pH can increase bacterial content in the pore and cause dryness and irritation (as stated above, this body lotion has a pH of 9). In all likelihood, the DMAE present in skin-care products cannot have any prolonged functionality (Source: Journal of Drugs in Dermatology, Supplement 72, 2008, pages S17–S22).
Without question there are some intriguing ingredients in Cold Plasma Body; it’s just not the breakthrough product it’s made out to be, and Perricone hasn’t published any research to support his claims.
The ingredient phosphatidylcholine (PC) in this formulation deserves some explanation. PC is the active ingredient in lecithin, and every cell membrane in the body requires PC. It also is a major source of the neurotransmitter acetylcholine. Acetylcholine is used by the brain in areas that are involved in long-term planning, concentration, and focus, but all of that information is associated with ingesting PC, not putting it on your skin. For topical application, PC is considered a very good water-binding agent and aids in the penetration of other ingredients into the skin. It also absorbs well without feeling greasy or heavy (although other ingredients perform similarly, including glycerin, ceramides, and hyaluronic acid) (Sources: Skin Pharmacology and Applied Skin Physiology, September-October 1999, pages 235–246; and Journal of Controlled Release, March 29, 1999, pages 207–214.)
Formulated with the revolutionary Cold Plasma technology, this formula helps to reduce wrinkles and the crepey look of skin with DMAE. It delivers superb hydrating, plumping, and smoothing benefits with Sodium Hyaluronate and minimizes the appearance of cellulite with concentrated levels of caffeine. It gives arms and legs a beautiful defined and contoured appearance and is shown to improve the appearance of cellulite and dimpled skin on thighs, buttocks, and arms.
Water, Dimethyl MEA (DMAE), Isopropyl Palmitate, Glycolic Acid, L-Tyrosine, Cetearyl Alcohol, Phosphatidylcholine, Acetyl Carnitine Hcl, Arginine, Hydroxylated Lecithin, Limnanthes Alba (Meadowfoam) Seed Oil, Glyceryl Stearate, PEG-100 Stearate, Thioctic Acid (Alpha-Lipoic Acid), Caffeine, Ceteareth-20, Dimethicone, Magnesium Aspartate, Zinc Gluconate, Rhodiola Rosea Root Extract, Phenoxyethanol, Polyglyceryl-10 Pentastearate, Elaeis Guineensis (Palm) Oil, Caprylyl Glycol, Behenyl Alcohol, Saccharomyces Ferment, Tocotrienols, Carnosine, Disodium EDTA, Sodium Hyaluronate, Tocopherol, Sodium Stearoyl Lactylate, Astaxanthin, Fragrance, Copper Gluconate, Sorbic Acid, Limonene, Linalool, Alanyl Glutamine.
This dermatologist-developed line is perhaps the best known in an increasingly crowded field. The frenzy began with Nicholas Perricone's first book, The Wrinkle Cure, and continued when he appeared on PBS to discuss his book and namesake products, all of which seemed incredibly legitimate to consumers worried about how to look younger longer. PBS reaped a financial windfall from his appearance, netting millions of dollars between 2001 and 2002 (Source: www.quackwatch.org). Originally all the fuss centered around vitamin C and alpha lipoic acid, but as his success continued, Perricone wrote half a dozen more books and expanded his product line to include other over-hyped ingredients, each with claims (and price tags) more inflated than the last round.
We sourced the Web site Quackwatch.org because they have an excellent, unbiased report on the Perricone phenomenon. This non-profit site is operated by consumer advocate Dr. Stephen Barrett, and, to quote the Quackwatch Mission Statement, their purpose is "to combat health-related frauds, myths, fads, fallacies, and misconduct." That's where Perricone comes into play. According to Quackwatch, Perricone's books "contain many claims that are questionable, controversial, fanciful, unsupported by published evidence, or just plain wrong. Although he mentions standard skin-care treatments, sometimes favorably, his books provide little guidance about when they might be appropriate or sufficient. Although he provides long lists of references, practically none of them directly support what he promises." Those sentiments are exactly what we felt and wrote after reading The Wrinkle Cure.
The site goes on to state: "Perricone's books are sprinkled with statements that his ideas are based on his own research. However, the extent and quality of this research is unclear. A PubMed search for his name brought up only six citations, of which only two appear to be original research, both on topical glycolic acid. His books describe situations in which he tested various ideas in a few patients, usually over a short period of time, but he provides few details and apparently published none of those findings in medical journals." Does that sound like the kind of products you'd like to spend (a lot of) your money on?
They go on to conclude (and we agree completely with the following text): "Dr. Perricone has mixed a pinch of science with a gallon of imagination to create an elaborate, time-consuming, expensive, prescription for a healthy life and younger skin. There is no reason to think his program is more effective than standard measures. Although some of his advice is standard, most of his recommendations are based on speculation and fanciful interpretation of selected medical literature. He makes lots of money by convincing patients and consumers, but he hasn't succeeded in convincing critical thinkers, doctors, scientists, or anyone who wants to see hard evidence. Perricone's prescription isn't science; it's creative salesmanship." And which ingredient is the answer for healthy skin? Perricone can't seem to make up his mind, because one group of products contains alpha lipoic acid, another group olive oil, another vitamin C, and still another neuropeptides. Come on, doctor, which is it?
One ingredient Perricone uses deserves some discussion because it is present in all of his products, and that's dimethyl MEA, also known as DMAE (chemically 2-dimethyl-aminoethanol). DMAE has been around for years as an oral supplement that's popularly believed to improve mental alertness, much like Ginkgo biloba and coenzyme Q10. However, the research about DMAE does not show the same positive results as the other two supplements. Because DMAE is chemically similar to choline, DMAE is thought to stimulate production of acetylcholine. And because acetylcholine is a brain neurotransmitter, it's easy to see how it could be associated with brain function. However, only a handful of studies have looked at DMAE for that purpose and they have not been conclusive in the least, while some have shown that DMAE may be problematic or not very effective (Sources: Mechanisms of Aging and Development, February 1988, pages 129–138; Neuropharmacology, June 1989, pages, 557–561; European Neurology, 1991, pages 423–425; and European Journal of Medical Research, May 2003, pages 183–191).
How does any of this translate into skin care, or, more to the point, suppressing the signs of aging? Perricone claims DMAE restores muscle tone to skin that has lost firmness and has begun to slacken, as well as conveying an antioxidant benefit. Johnson & Johnson uses DMAE in a few of their Neutrogena products, and a study they paid for appeared in the American Journal of Clinical Dermatology (June 2005, pages 39–47). The conclusion was as follows: "the benefits of DMAE in dermatology include a potential anti-inflammatory effect and a documented increase in skin firmness with possible improvement in underlying facial muscle tone." The study examined topical application of 3% DMAE over a period of 16 weeks, but it was not done double-blind and was not placebo-controlled, which makes the results, at best, questionable. Moreover, the study didn't examine whether a 3% or lower concentration of other ingredients, such as green tea, glycolic acid, vitamin C, or myriad others (many of which Perricone has extolled in his other products, and the amount of DMAE he used varies widely from product to product), might have had the same or better results.
Is there any reason to get excited (and drain your pocketbook) for products with DMAE? Apparently not; a study published in The British Journal of Dermatology (May 2007) has shown contrary evidence that it may actually pose risks for the skin. In vitro tests of the pure substance, as well as creams that contained DMAE, demonstrated a fairly fast and significant increase in protective elements around the skin cell. However, a short time later the researchers observed an important reduction in cell growth and in some cases they found that it halted cell growth altogether. So, while you may initially experience a kind of swelling of the skin because of the expanding effect caused by topical application of DMAE, the long-term results appear to be far from desirable.
Interestingly, even though this ingredient is present throughout Perricone's line, he has yet to publish his own research discussing the claims and explaining how topical DMAE works. The bottom line is that as more research comes to light, DMAE may prove more problematic than helpful for aging skin. But in the meantime, Perricone is raking in lots of money by convincing consumers otherwise.
For more information about Perricone MD Cosmeceuticals call (888) 823-7837 or visit www.perriconemd.com.