If you’re hoping that spending this much will finally get you the best body moisturizer ever, prepare to be disappointed: Intensite Creme Supreme is not worth its eyebrow-raising price tag, although we imagine that some of the ladies who shop Nieman Marcus, where this line is primarily sold, won’t even notice.
Yes, this does have a lush, rich texture and contains many ingredients suitable for dry skin; however, the fact that it’s packaged in a jar means the beneficial ingredients won’t remain stable once it is opened. All plant extracts, vitamins, antioxidants, and other state-of-the-art ingredients break down in the presence of air, so once a jar is opened and lets the air in, these important ingredients begin deteriorating. Jars also are unsanitary because you’re dipping your fingers into them with each use, adding bacteria, which further deteriorate the beneficial ingredients. For what this body moisturizer costs, you should expect (and get) packaging that keeps key ingredients stable during use.
One ingredient in this product deserves further comment, and that’s recombinant IGF. “Recombinant” refers to genetically manipulating an ingredient. The IGF stands for insulin-like growth factor. Like most growth factors, IGF plays an important role in cellular growth, division, and survival. Perhaps the most important thing for you to know is that although there definitely is research showing IGF has benefit in wound healing (Sources: Development, March 2010, pages 871–879; Journal of Plastic, Reconstructive, and Aesthetic Surgery, December 2009, pages e364–e369; Wound Repair and Regeneration, July 2003, pages 253–260; and The Journal of Immunology, June 2003, pages 5583–5589), there is little to no research showing it to have a benefit for healthy skin or wrinkles (wrinkles are not wounds).
What research does exist is controversial and was not conducted using pure insulin-like growth factor, but rather an ingredient said to stimulate its production in skin by virtue of controlled irritation (Sources: Bioscience, Biotechnology, and Biochemistry, April 2010, pages 759–765; Current Medicinal Chemistry, volume 15, 2008, pages 3095–3112; Growth Hormone & IGF Research, August 2008, pages 335–344; and New England Journal of Medicine, February 27, 2003, pages 777–778). Repeated irritation has its own issues.
Other than ReVive’s founder, Dr. Greg Brown, no one seems to think much of using IGF for wrinkles, and the concern that it may be problematic is not trivial because overuse of growth factors can cause the type of cell proliferation that’s the blueprint for cancer. However, we don’t think you need to be worried, because the amount of IGF in this product is minuscule and the type of packaging makes stability practically impossible once it’s opened.
Powered by RES and Glycolic Acid, this intensively hydrating body cream helps strengthen skin while improving elasticity. Skin tone and texture are evened and enhanced as the visible signs of aging -- spots, dryness, even stretch marks – are dramatically diminished.
Water, Propylheptyl Caprylate, Caprylic/Capric Triglyceride, Cetyl Alcohol, Glycerin, Glycolic Acid, Squalane, Glyceryl Stearate, Olea Europaea (Olive) Fruit Oil, Hydrogenated Olive Oil, PEG-100 Stearate, Recombinant IGF, Bisabolol, Tocopheryl Acetate, Sodium PCA, PEG-4, Hydroxycinnamic Acid, Allantoin, Saccharomyces Lysate Extract, Methylsilanol Hydroxyproline Aspartate, Dimethicone, Candelilla/Jojoba/Rice Bran Polyglyceryl-3 Esters, Cetearyl Alcohol, Sodium Stearoyl Lactylate, Behenyl Alcohol, Palmitic Acid, Stearic Acid, Lecithin, Lauryl Alcohol, Myristyl Alcohol, Polyacrylate-13, Polyisobutne, Polysorbate 20, Xanthan Gum, Sodium Hydroxide, Magnesium Aluminum Silicate, Benzyl Salicylate, Citronellol, Hexyl Cinnamal, Butylphenyl Methylproprional, Limonene, Linalool, Phenoxyethanol, Caprylyl Glycol, Chlorphenesin, Fragrance.
Without a doubt, the founder of ReVive, Dr. Gregory Bays Brown, has some impressive credentials. He is a board-certified general and plastic surgeon who trained at Vanderbilt, Harvard, and Emory Universities, and received his medical degree from the University of Louisville. Realizing there was considerable money to be made in the realm of doctor-designed skin care, he launched the ReVive brand in the late 1990s, and it is now known as "A Plastic Surgeon's Non-Surgical Approach to Beauty."
It is nothing less than perplexing that there are so many doctors, from Fredric Brandt to N.V. Perricone, Drs. Murad and Sobel, and Patricia Wexler, to name a few, all claiming that their skin-care products are the answers for aging consumers who are concerned about "going under the knife" or about making an appointment that involves use of a needle. Can every doctor cure your wrinkles? And which one is telling the truth? Simply put: None of them. What they are doing, to one degree or another, is misleading the consumer as to what their products can really do, and every physician on the planet knows this to be a fact.
Brown does have one point of difference from his competition because he is the only one who uses growth factors (GF) in all his products. He was originally all about Epidermal Growth Factor (EGF), explained below, but now also offers products with Insulin-like Growth Factor (IGF) and Keratinocyte Growth Factor (KGF), each explained in their respective product reviews. With all the company's talk about speeding up cellular renewal via growth factors and promises of luscious, dewy, youthful-looking skin, you may be wondering if this is a group of ingredients worth paying (a lot of money) for.
Growth factors are produced by the body to regulate various types of cell division. EGF stimulates cell division, primarily cell division of skin cells. There is quite a bit of research showing EGF to be helpful for wound and burn healing (Sources: Journal of Burn Care and Rehabilitation, March-April 2002, pages 116–125; Journal of Dermatologic Surgery and Oncology, July 1992, pages 604–606; Journal of Anatomy, July 2005, pages 67–78; International Wound Journal, June 2006, pages 123–130;and Tissue Engineering, January 2007, pages 21–28).
However, there is also research showing the effect EGF has is no different from that of a placebo, that it may not be effective at all, and that too much of it can actually prolong healing (Sources: Wounds, 2001, volume 13, number 2, pages 53–58; and Plastic and Reconstructive Surgery, August 1995, pages 251–254, and September 1997, pages 657–664).
One study showed that EGF had anti-inflammatory properties when applied to skin (Source: Skin Pharmacology and Applied Skin Physiology, January-April 1999, pages 79–84), though it has also been noted that it may promote tumor growth (Source: Journal of Surgical Research, April 2002, pages 175–182).
In general, the potentially frightening consequences of growth factors can come into play when they are taken internally, as in certain cancer treatments (Interleukin and Interferon are GFs), because they can be highly mitogenic (causing cell division), and at certain concentrations and lengths of application can cause cells to overproliferate. This overabundance of cells causes problems, one result of which is cancer. No one is exactly certain what happens when EGFs are applied to healthy, intact skin, but there is concern that with repeated use EGFs can cause skin cells to overproduce, and that's not good (psoriasis is an example of what happens when skin cells overproduce).
All of the research that does exist on EGFs has primarily studied their short-term use for wound healing. ReVive's products aren't about wound healing or short-term use, but rather about ongoing application for wrinkles, and working against the reduced cell-turnover rate that occurs as we age. Moreover, what established research has shown (including most of the sources mentioned above) is that growth factors, including EGF, do not work alone. Rather, their function is part of an intricate symphony that requires the playing of several "notes" for the "concert" to be a success. Adding a tiny amount of EGF to skin-care products in the hopes that it will work like it does when applied to a wound is sort of like thinking you can frame a house with wood and use nothing to hold the beams together except wishful thinking. We suspect the EGFs that Brown uses are most likely not the active form of the "drug," because if they were the risk to skin would be scary (and the company admits the ingredient is engineered in a lab, which means it's not identical to the naturally occurring EGF).
For more information about ReVive, call 1-866-986-7083 or visit www.reviveskincare.com.