Signs Wrinkle Serum (Discontinued)
1 fl. oz. for $175
Category:Skin Care > Serums > Serums
Last Updated:03.18.2015
Jar Packaging:No
Tested on animals:Yes
Review Overview

This serum contains an impressive mix of water-binding agents, cell-communicating ingredients, antioxidants, non-fragrant plant oil, and other helpful ingredients that all skin types need. The texture of this serum enables it to serve as a sort of soft spackle for lines, but the effect is fleeting, and, once again, you can get the same effect from many other products that cost less—a lot less—than this. This fragrance-free serum is suitable for all skin types. It is similar to, but has a more elegant formula than, serums from the Olay Regenerist line. It pains us to rate this serum among the best, because in no way do we believe even half the hype with SK-II's star ingredient Pitera, a strain of yeast. Supposedly, monks who lived in the mountains somewhere used it to make their rice wine and subsequently their skin maintained its youthful appearance. We ask you: Who comes up with this insanity and why do so many women believe it?


This unique serum combines Pitera and a ‘fill and plump complex’ which includes Vitamin B3, which work together to help reduce the appearance of the length and depth of wrinkles, seemingly filling and shortening to create the appearance of smooth, younger looking skin.


Water, Cyclopentasiloxane, Glycerin, Saccharomycopsis Ferment Filtrate, Dimethicone, Niacinamide, Pentylene Glycol, Acetyl Glucosamine, Butylene Glycol, Polyethylene, Panthenol, Acetyl Tetrapeptide-9, Tocopheryl Acetate, Tocopherol, Sodium Hyaluronate, Oryza Sativa (Rice) Germ Oil, Saccharomyces Cerevisiae Extract, Haematococcus Pluvialis (Astaxanthin) Oil, Dimethicone/Vinyl Dimethicone Crosspolymer, Polyacrylamide, PEG-11 Methyl Ether Dimethicone, C13-14 Isoparaffin, Dimethiconol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Laureth-7, Sodium Hydroxide, Benzyl Alcohol, Methylparaben, Disodium EDTA, Sodium Benzoate, Phenoxyethanol, Ethylparaben

Brand Overview

SK-II At-A-Glance

Strengths: Some well-formulated moisturizers and serums; all of the sunscreens provide sufficient UVA protection.

Weaknesses: Shockingly expensive, especially for the wide assortment of mediocre products; unreliable skin-lightening products; AHA/BHA products that contain an ineffective amount of exfoliant; no products to help manage blemishes; jar packaging.

Procter & Gamble, as always, is extremely helpful in providing information about their products. In this case it was for their upscale SK-II skin-care line. We certainly can't say that about most companies. We have to acknowledge P&G for having the integrity to share their "inside" details with someone like me, who might be more critical than complimentary. Thank you, P&G!

Regrettably, and we mean that sincerely, we wish we had more positive comments to convey, but alas, we don't. The data provided don't change the reality about skin care and the ingredients that can have an impact on skin. SK-II products are hardly worth the price, especially when compared to Olay Regenerist and Definity (P&G's own drugstore line of skin-care products). In fact, it takes only a quick review of the formulas to note that many SK-II items are very similar to Olay Regenerist items, except that the latter don't include Pitera, the supposedly miracle ingredient in this line. Yet there is minimal research indicating that Pitera is even helpful for skin.

Pitera is the cornerstone of the SK-II line and is present in every SK-II product. Pitera is the trade name for Saccharomycopsis ferment filtrate (SFF), a form of yeast purportedly unique because of the fermenting and filtering process it goes through before being added to these products. As it turns out, many forms of yeast have anti-inflammatory properties and antioxidant properties, including SFF (Source: Journal of Dermatologic Science, June 2006, pages 249–257). Other than that, all of the information about Pitera comes from papers presented at medical conferences, not from published studies. Presenting papers at medical conferences is not at all the same thing as publishing the results of studies. We frequently present papers and information at medical conferences, and we wouldn't offer that material as proof of anything because it isn't. The standards for presenting a paper at a medical conference are very different from the requirements for publication of study results in most medical journals.

To give P&G the benefit of the doubt, even if Pitera is a wonder ingredient, this doesn't explain how it rates when compared with other "wonder" ingredients because there are no comparison studies. Hundreds of ingredients—ranging from green tea to superoxide dismutase, epigallocatechin-3-gallate, eicosapentaenoic acid, beta-carotene, pomegranate, and curcumin to vitamin E, vitamin A, and on and on and on—have stellar reputations, and there's copious documentation to prove it.

Another point to consider: If Pitera deserves the spotlight SK-II shines on it, then P&G needs to change their claims about Olay Regenerist and Definity, and at the very least say that these products are almost as good as SK-II except we left out the Pitera. Ultimately, unless you believe Pitera is the answer for your every skin-care need (because each and every SK-II product contains it, with very few other added extras), there is no reason to waste your time and energy on this line.

For more information about SK-II, owned by Procter & Gamble, visit www.sk-ii.com.

About the Experts

The Beautypedia Research Team is dedicated to helping you find the absolute best products for your skin, using research-based criteria to review beauty products from an honest, balanced perspective. Each member of the team was personally trained by Paula Begoun herself.

Member Comments
Summary of Member Comments
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This is a wonderful product and has definitely help with lines on my forehead. As far as hype, everyone has to find a product that ultimately works for their skin-type. Also, regarding price, if you have it......

Reviewed by
Brian, D
Right on

This cosmetics cop review is right on and the last sentence in the review is hilarious! I laughed out loud when I read it. Thank you!

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