Ossential Advanced Radical Night Repair
2 fl. oz. for $170
Last Updated:12.18.2014
Jar Packaging:No
Tested on animals:No
Review Overview

This silky, silicone-based retinol serum has been reformulated to eliminate the ingredients we called out as being a problem. That's great news, though we're still on record stating that this serum's price is too high, and definitely more than you need to spend to get a high-potency retinol product. Still, there's no denying its an impressive formula, hence its rating.

How much retinol this repair treatment contains isn't revealed, but the previous version had 1%, and there's no reason to suspect this contains any less than that. Retinol at 1% is definitely potent, something Zo Skin Health is aware of based on the precautionary statements accompanying this product.

Best for normal to dry skin not prone to breakouts, Ossential Advanced Radical Night Repair contains some smoothing, non-fragrant plant oils (including a peanut oil listed by its Latin name of Plukenetia volubilis. Also on hand are two forms of vitamin E, a tiny amount of vitamin C (ascorbyl palmitate), and novel plant extracts that likely have water-binding and antioxidant benefits for skin. This is a fragrance-free product, which is what you want given fragrance-free is best for skin and high-strength retinol products require a gentle formula in order to minimize the risk of side effects 1% retinol can have.

You don't need to spend this much to get a potent retinol treatment that can fight multiple signs of aging, but this is one to consider and its current formula is MUCH better than the original version, for what was removed and for the good stuff that was added!


A lightweight, high potency retinol formula that targets multiple signs of aging skin while protecting against future skin aging and damage. Moderate reaction.


Cyclopentasiloxane, Dimethicone Crosspolymer, Dimethicone, Prunus Amygdalus Dulcis Oil, Glycerin, Polysorbate 20, Water (Aqua), Retinol, Cyclotetrasiloxane, Diisopropyl Adipate, Plukenetia Volubilis Seed Oil, Oleyl Alcohol, Phenoxyethanol, Tocopheryl Acetate, Helianthus Annuus Seed Oil, BHT, Chlorphenesin, Leontopodium Alpinum Meristem Cell Culture, Marrubium Vulgare Meristem Cell Culture, Zanthoxylum Bungeanum Fruit Extract, Sodium Sulfite, Caprylyl Glycol, Ascorbyl Palmitate, Gluconolactone, BHA, Rosmarinus Officinalis Leaf Extract, Sodium Benzoate, Lecithin, Xanthan Gum, Parfum, Tocopherol, Ascorbic Acid, Zea Mays Oil, Beta-Carotene.

Brand Overview

Zo Skin Health

Strengths: Company provides complete ingredient lists on the Zo Skin Health Web site; good cleansers and scrubs; very good fragrance-free mineral sunscreen; all of the body-care products; the sunscreens provide sufficient UVA protection and include a mineral-based formula for those with sensitive skin or rosacea; some very good moisturizers and serums.

Weaknesses: Can be expensive; some products contain fragrance chemicals known to cause irritation; some jar packaging.

The ZO in ZO Skin Health is the initials of this line's creator, dermatologist Dr. Zein Obagi. It’s not the first skincare line for the Beverly Hills-based doctor; you may recall Obagi, his original namesake skin-care line, which initially was sold only in physicians' offices. After several years with the brand, Obagi left and founded a new line, ZO Skin Health.

This newer line actually makes improvements upon Obagi’s initial foray into skincare, with distinctly better formulas than similar products in the original Obagi line. For the most part, this line does a good job of offering consumers formidable options to improve the appearance of skin and (in the case of sunscreens) to prevent further damage to aging skin. This is a worthwhile line if you're looking for products with retinol that also contain other state-of-the-art ingredients (most retinol products are one-note formularies).

The body-care products are also a cut above, though they’re not the easiest on the pocketbook. However, there are less expensive options, so there's no need to worry if you can't afford this line. Zo Skin Health is not one-stop shopping for all manner of sun-damaged or aging skin and it also isn't comprehensive enough to meet everyone's needs and preferences. However, formula- and appearance-wise it bests much of what was offered in his original line.

For more information about Zo Skin Health, call 888-893-1375 or visit www.zoskinhealth.com.

About the Experts

The new Beautypedia Team proudly and unequivocally maintains the commitment to help you find the best products possible for your skin. We do this by relentlessly pursuing and relying on published scientific research so you will have unbiased information on what works and what doesn't-and the sneaky ways you could be making your skin worse, not better!

The Beautypedia Team reviews all products using the same research, criteria, and objectivity, whether the product being reviewed is from Paula's Choice or another brand.

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