Synthetically derived peptide that is used in a wide range of skincare and makeup products.
Despite claims being made for acetyl hexapeptide-8 (argireline), there is a clinical study revealing that this ingredient is not even remotely as effective as dermatological procedures in reducing signs of aging. [1,2]
Still, like all peptides, acetyl hexapeptide-8 has water-binding properties and theoretical skin-restoring ability. It’s not a throwaway ingredient, but neither is it as miraculous as the manufacturer would lead you to believe.
- Blanes-Mira C, Clemente J, Jodas G, Gil A, Fernández-Ballester G, Ponsati B, Gutierrez L, Pérez-Payá E, Ferrer-Montiel A. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002;24(5):303-10.
- Lupo M, Cole A. Cosmeceutical peptides. Dermatol Ther. 2007;20(5):343-9.