licorice extract

Rating:
Best
Categories:
Plant Extracts , Anti-Irritants

Plant extract that has anti-inflammatory properties. [1] In addition, licorice root contains constituents that interrupt the stimulation of an enzyme that activates melanin production, so this part of the plant can be effective for improving dark spots and hyperpigmentation. [2,3]

Licorice has shown to have efficacy against acne-causing bacteria. One of its components, known as glabridin, is a potent antioxidant and anti-inflammatory ingredient, which is why licorice often shows up in products meant for sensitive, reddened skin. [4,5]

Licorice extract has several active compounds that may stimulate or suppress the formation of melanin. According to one study, "Glabridin, the main ingredient in the hydrophobic fraction of licorice extract, inhibits tyrosinase activity in cultured B16 murine melanoma cells, at concentrations from 0.1 to 1.0 µg ml-1, without affecting DNA synthesis. Other active compounds, such as glabrene, isoliquiritigenin licuraside, isoliquiritin, and licochalcone A, isolated from licorice extracts, were also shown to inhibit tyrosinase activity."[6]

References Cited:

  1. Rahnama M, Mehrabani D, Japoni S, Edjtehadi M, Saberi M. The healing effect of licorice (Glycyrrhiza glabra) on Helicobacter pylori infected peptic ulcers. J Res Med Sci. 2013;18(6):532-533.
  2. Ebanks J, Wickett R, Boissy R. Mechanisms Regulating Skin Pigmentation: The Rise and Fall of Complexion Coloration. Int J Mol Sci.. 2009;10(9):4066-4087.
  3. Davis E, Callender V. Postinflammatory Hyperpigmentation. J Clin Aesthet Dermatol. 2010;3(7):20-3.
  4. Simmler C, Pauli G, Chen S. Phytochemistry and biological properties of glabridin. Fitoterapia. 2013;90:160-84.
  5. Veratti E, Rossi T, Giudice S, Benassi L, Bertazzoni G, Morini D, Azzoni P, Bruni E, Giannetti A, Magnoni C. 18beta-glycyrrhetinic acid and glabridin prevent oxidative DNA fragmentation in UVB-irradiated human keratinocyte cultures. Anticancer Res. 2011;31(6):2209-15.
  6. Wenyuan Z, Jie G. The use of botanical extracts as topical skin-lightening agents for the improvement of skin pigmentation disorders. J Investig Dermatol Symp Proc. 2008;13(1):20-4.
See glycyrrhetic acid

«Back to Ingredient Dictionary

About the Experts

Paula Begoun is the best-selling author of 20 books on skin care and makeup. She is known worldwide as the Cosmetics Cop and creator of Paula's Choice. Paula's expertise has led to hundreds of appearances on national and international television including:

View Media Highlights

The Paula's Choice Research Team is dedicated to busting beauty myths and helping you solve your skincare frustrations with research-supported expert advice—so you'll have the facts you need to take the best possible care of your skin.

Skip to Top of Page

Free Email Sign-Up

- (Less Frequent)
- Expert Advice Newsletter (twice a month)
- New reviews on Beautypedia (twice a month)

Birthday (Fill out to receive a birthday surprise)

 

NEVER RUN OUT AGAIN

Paula’s Choice Auto Delivery is a quick and convenient way to make sure you never run out of your favorite products again. Just select the products you can’t live without, choose how often you’d like them delivered and we’ll take care of the rest.

Get 10% off your first order when you sign up today.