Cell-Communicating Ingredients

A synthetic peptide with the "tri" (meaning three) designation referring to this peptide's mix of the amino acids proline, serine, and threonine. According to the patent filed for this peptide, it's somehow supposed to interact with skin's repair process as related to its circadian rhythm. It is said to be able to turn on and turn off genes in skin responsible for repair at key times of the day and night (never mind the fact that skin is working to repair itself around the clock). There's no independent research proving this is true or explaining how this ingredient can penetrate far enough into skin to alter cellular function in terms of controlling the activity level of genes, plus the whole notion borders on drug rather than cosmetic claims. Needless to say, what sounds good in theory or on paper doesn't always pan out in real-world testing. At this time tripeptide-32, like most other peptides, has theoretical cell-communicating ability and likely serves to bind moisture to skin, but all other fantastic-sounding claims remain in the realm of a petri dish or are simply unproven or unknown.

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About the Experts

Paula Begoun is the best-selling author of 20 books on skin care and makeup. She is known worldwide as the Cosmetics Cop and creator of Paula's Choice. Paula's expertise has led to hundreds of appearances on national and international television including:

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The Paula's Choice Research Team is dedicated to helping you find the absolute best products for your skin, using research-based criteria to review beauty products from an honest, balanced perspective. Each member of the team was personally trained by Paula herself.

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