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Clinical 1% Retinol Treatment

Sun damage that won't go away? Wrinkles keeping you up at night? Don't get mad, get powerful.
Item #: 801
  • Acne Breakouts, Anti-Aging, Brown Spots, Wrinkles
  • For All Skin Types
  • Firms skin, smoothing deep wrinkles and fine lines
  • Reduces dark spots and uneven skin tone, refines pore size

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Customer Ratings:

88 out of 100
(Based on 173 Reviews)
Page of 7 Next »
  1. Julia N.
    Reviewed on Thursday, March 19, 2015
    100 out of 100
    • Rating
      Best / 4
    I am so glad I found this!
    • I couldn't believe how nice this felt in combination with the oil. My skin just loves it! It gets absorbed completely and I never have any adverse effects. I feel my skin is getting firmer and more even toned already even though I only used it for a couple of months (not every day though). I started out slow because I really didn't want to have a reaction to this. I used it only twice a week for the first couple of weeks; now I am using it every other day and I love it. I highly recommend it!

  2. Julia H
    Reviewed on Wednesday, March 18, 2015
    100 out of 100
    • Rating
      Best / 4
    HG
    • I got the trial with the trial Oil Booster, I don't think my skin has ever looked better. I'm in my mid-20s and struggle with acne and dry skin with an uneven complexion. After one use two large and painful spots were almost completely annihilated. Five uses and my skin tone is more consistent, acne is minimal and not as painful, and the texture of my skin is vastly improved. I feel like I could leave the house without makeup and not hide from other people. No negative side effects so far.

  3. Peggy R.
    Reviewed on Monday, March 16, 2015
    100 out of 100
    • Rating
      Best / 4
    I love this product
    • I have use this skin treatment for just 3 days and have already seen a great improvement in my skin tone. Its already become firmer and the wrinkles around my mouth have dramatically improved. My only thought when first seeing the product is the packaging. Why have the product in such a superior package and give just one ounce of treatment ? I and I think most people would rather have more of the product (2 0z.) in just a simple jar. This product is great and will sell itself :)

  4. Francie
    Reviewed on Sunday, March 15, 2015
    100 out of 100
    • Rating
      Best / 4
    A++
    • THIS STUFF IS POWERFUL. I started using Paula's Choice 5 years ago to help with my very complicated and breakout-prone skin. PC products got my skin to about 80% perfect, I still had a breakout about every six weeks or so. The Clinical retinol has been the magic product to get me that last 20%. My skin has been clear ever since I started using this in October. It was the final oomph my routine needed. I love this stuff!

  5. TERESE L.
    Reviewed on Friday, March 13, 2015
    100 out of 100
    • Rating
      Best / 4
    Best treatment
    • This is the best skin care product I have ever used. I followed the instructions and started out using it once every other day. I didn't experience any irritation, so moved to using it every night. My skin is clear, smooth, glowing, bright... everything I could ask for. After seeing what this did for my skin in just a few months, I am convinced that every woman should be using a retinoid based product like this one.

  6. Lucia
    Reviewed on Tuesday, March 10, 2015
    100 out of 100
    • Rating
      Best / 4
    Effective
    • I use this every other night over the PC Oil. The oil buffers the retinol and allows the pea-sized amount I use to spread easily. I am noticing that my skin is a lot smoother on this regimen. Due to the potency of this retinol I have stopped any other PC products that also contain retinol and this is working well. I am 53 and appreciate having a product that is so effective at encouraging cell turnover.

  7. jen
    Reviewed on Saturday, March 07, 2015
    100 out of 100
    • Rating
      Best / 4
    great product
    • My skin used to be really bad. Huge pores, oily, blackheads. Started this, it was rough for nearly two weeks. Flaky, peeling skin. But then, finally the skin I've always wanted. I still have pores, visible, but they are much smaller. Blackheads reduced, 2% BHA did not work on those. I were less makeup, with less touch ups throughout the day. I typically take a week or two off, then start again. Will never be without if I can afford it.

  8. Angela C.
    Reviewed on Friday, March 06, 2015
    40 out of 100
    • Rating
      Poor / 4
    Tried, disappointed
    • I wanted this product to work for me but it just does not. I used after getting accustomed to the resist with retinol moisturizer, thinking that since my skin has been responding well that I could ramp up the retinol %. Unfortunately, every time I use this I break out on my sensitive skin areas: on my nose and upper/outer lip area. And I have never had acne or been prone to breakouts! Sorry to have to give a bad review, however if you have pale, dry-ish, thinner skin, order the sample first

    Customer Service Response
    Replied on: Monday, March 09, 2015

    Hello, and thank you for sharing your experience with us - we're sorry to hear this didn't work as expected for you! Please contact a member of our Customer Care team, who can assist you with a possible exchange or refund.

    —Paula's Choice Research Team
  9. KK
    Reviewed on Thursday, March 05, 2015
    100 out of 100
    • Rating
      Best / 4
    Great under makeup!
    • I used to use Retin-A Micro gel on my nose and cheeks (for pores) in the morning, but I almost always had to then wipe it off before putting on makeup, no matter how long I waited or how little I used. When I received this as a sample, I tried it instead, and it works wonderfully under makeup. I've never seen any results from my years of using prescription R-A Micro, despite all the studies, but for some reason this product has made my pores look better already!

  10. Janna K.
    Reviewed on Thursday, March 05, 2015
    100 out of 100
    • Rating
      Best / 4
    Retin A results without the Retin A
    • I've used Retin A and Retin A Micro for acne on and off over the past two decades. My Paula's Choice regimen including this clinical strength retinol product, 2% Clear Regular Strength BHA, and 2.5% Clear Benzoyl Peroxide has given me better results. I break out so rarely, that I almost forget that I have acne. The routine has eliminated my breakouts and faded past marks. That being said, start slow with this product because it is STRONG. Mix it with your moisturizer and/or Paula's Oil Booster.

  11. Christina S.
    Reviewed on Sunday, March 01, 2015
    100 out of 100
    • Rating
      Best / 4
    Wonderful product
    • I have been using this product on my oily skin and adult hormonal acne for 2 months. My acne has significantly decreased, red marks have faded, and skin appears smoother. The last time my skin was this good was years ago when I was using Retin-a micro; this product does just as good of a job if not better. I still only use it every other night due to flaking, but the Skin Recovery Toner and Resist Oil Booster mixed with my regular moisturizer do a great job of calming and hydrating my skin.

  12. Elisabeth B
    Reviewed on Saturday, February 28, 2015
    100 out of 100
    • Rating
      Best / 4
    Try with the clinical oil for perfect skin!
    • I had a reaction to this at first which was very disappointing but I added a couple of drops of the Clinical Oil to the mix and the results are fabulous. I have been thrilled when my younger sisters have insisted I've had Botox as I am 35 and 100% wrinkle free thanks to obsessive use of sunscreen and Paula's products and advice but adding this to the mix has taken my skin to the next level!

  13. Anonymous
    Reviewed on Friday, February 27, 2015
    100 out of 100
    • Rating
      Best / 4
    Very well made product
    • I have a very love/hate relationship with Paula's choice mostly stemming from the fact that I feel some of the reviews are too harsh. That said, this product costs more than my prescription strength Retin-A & I was looking for something to alternate with my strong Retin-A Rx. I decided to give this and the Ultra-Rich Moisturizer a try despite my feelings. The experience was fantastic and my skin has been glowing since. It was worth every penny and has been very elegantly formulated. A winner.

  14. Janet, H
    Reviewed on Thursday, February 26, 2015
    100 out of 100
    • Rating
      Best / 4
    Keep Trying- Worth It!
    • Morn and night I use Paula's Clear Acne Wash, BHA 2%, and 5% Benz Peroxide. Added Retinol 1% at night. I started slowly/ used every 2-3 days- but had tons peeling. I tried not using B peroxide at night with Retinol, but then broke out and still peeled. Next I added back B Peroxide and skip the BHA at night- Now I can use the Retinol every night- no irritation. No breakouts. My Routine~No Peel or acne Every Morn: Wash, BHA, B Perox, Sunscreen Every Night: Wash, B Peroxide, Retinol

  15. Tara T
    Reviewed on Sunday, February 22, 2015
    100 out of 100
    • Rating
      Best / 4
    Only buy this if you want perfect skin
    • Wow. I don't think I have every been more pleased with a product. I purchased the sample size of this product 3 weeks ago and have been using it almost daily since. (So I have gotten at least 3 weeks worth of almost daily use out of the sample size). This product has truly delivered it's promises for my skin. My skin is clear, smooth, my lines s are SO much softer and the amount of makeup I am wearing is decreasing week by week. I can't wait to see the results going forward! Thanks, Paula!

  16. Marilyn
    Reviewed on Tuesday, February 17, 2015
    100 out of 100
    • Rating
      Best / 4
    I am sold!
    • I am 64 and quite frankly haven't taken great care of my skin over the years. Always used moisturizers, but that is about it. About 6 weeks ago I started using several of the Resist products and the 1% retinal treatment. I can see a real difference. Yesterday a woman said to me, "wow, your skin looks great! I can't believe you are 64. Whatever you are doing for your skin, keep doing it!". I think I will!

  17. DW
    Reviewed on Wednesday, February 11, 2015
    100 out of 100
    • Rating
      Best / 4
    Impressive
    • I started using this after using the Skinceuticals retinol 1% product for almost two years. The price is similar for both products, but I got Paula's Choice version at a discount. That was the inspiration to try it. I am glad I did, and will use this retinol treatment going forward. This retinol treatment is easier to apply and it packs a bigger punch with additional beneficial ingredients beyond the retinol. This is a great retinol product that I would highly recommend.

  18. Arlyne A.
    Reviewed on Friday, February 06, 2015
    100 out of 100
    • Rating
      Best / 4
    My skin glows!
    • I just turned 65 and needed a skin care line to keep my skin as young and healthy looking as possible. When I first started using this product, I didn't like it at all and returned it. My skin was irritated and dry - and I still have oily skin at my age! I worked with a consultant and we changed up my toner and moisturizer and now I actually use this every night with no problems. My skin never looked better - it really glows - and so far, no new wrinkles!!

  19. Joe L.
    Reviewed on Wednesday, February 04, 2015
    20 out of 100
    • Rating
      Worst / 4
    Ruined my skin!!
    • I have used alot of skincare products in my life, but none have never gave me the reaction this product did. The first day i put this on my face turn red like a tomato and got a burning sensation on my face that lasted about 2 weeks. But my face is still red 1 month and 1 week later..... my skin is very pale but now it looks like i been permanently sunburned. it's very depressing to look in the mirror because of what did this to my face. i wish i had never put this on my face.My face is ruined

    Customer Service Response
    Replied on: Wednesday, February 04, 2015

    Hello, and thank you for sharing your experience with us - we're sorry to hear this didn't work for you as expected! Please contact a member of our Customer Care team, who can assist you with a possible exchange or refund.

    —Paula's Choice Research Team
  20. Stacy S
    Reviewed on Wednesday, February 04, 2015
    100 out of 100
    • Rating
      Best / 4
    A little advice
    • When I used Retin-A as a teenager the instructions said to wait 20 minutes before applying. Because the face is damp and freshly washed the product sinks in more deeply and can cause even more irritation. Try waiting 20 minutes before you use this product and maybe even try putting it over your moisturizer until you build up some tolerance. This has helped me with the Resist Intensive Wrinkle Repair Retinol Serum.

  21. Brett E.
    Reviewed on Sunday, February 01, 2015
    100 out of 100
    • Rating
      Best / 4
    must have
    • After learning the hard way to not apply too much or too often or around they eyes, I can say after my skin has kinda flaked and peeled it is sooo soft and beautiful. Usually use it only once a week and at night and then dont use any aha/bha for a few days after. Coconut oil has definently helped with the redness and peeling after use

  22. Erin R
    Reviewed on Wednesday, January 28, 2015
    100 out of 100
    • Rating
      Best / 4
    Great Retinol Product
    • I started using this product as my skin is sensitive to BHA and AHA exfoliation and I thought this might be an option to start working on my acne. It is amazing! I started very slow and even after using it for months I still only do a pea sized pump in my normal moisturizer, 3 times a week after normal cleansing and toning. I have found that if I use it without the moisturizer or more than 3 times a week, I will get some peeling, so stick to my schedule and keep an eye out for any dryness.

  23. Amy
    Reviewed on Sunday, January 25, 2015
    100 out of 100
    • Rating
      Best / 4
    Clinical Retinol 1%
    • The first several times I used this product, my face would be red and peeling the next day. I have had a terrible time with my skin the last year. Turning 40 and stress has made my skin break out with cystic acne, something I've never had. I stopped using this and would always come back to it. Finally, I stopped turning red and peeling. This product has cleared my cystic acne and make my skin look amazing. The red spots are finally fading. I am SO glad I stuck with it. Thank you!

  24. Christine B.
    Reviewed on Saturday, January 17, 2015
    100 out of 100
    • Rating
      Best / 4
    Worked with my sensitive skin
    • I have extremely dry, sensitive skin. I took PC's advice, and I combined this with the oil booster, and I had visible improvement without any redness or irritation. I've just been using it 3 times a week, and I skip the AHA and BHAs on the days I use it. I was a little scared to try it given the sensitivity of my skin, but I have been very pleased with the results.

  25. Jess
    Reviewed on Friday, January 16, 2015
    100 out of 100
    • Rating
      Best / 4
    Love!
    • I LOVE this. Super effective on cystic acne, closed comedones, visible inflammation. Only issue with it is the price! (Though it's still quite reasonable for such an effective retinol product.)

Page of 7 Next »

What makes this product unique?
Combined with potent antioxidants, Clinical 1% Retinol Treatment is specially formulated to smooth and firm skin by helping to boost cell regeneration and stimulate collagen production. Its light, silky texture absorbs quickly and goes to work immediately to refine pore size, reduce deep wrinkles, fine lines, brown spots—it can even help breakouts, too! Licorice, oat extract and other anti-irritants help to minimize the irritation some people may get from products containing high amounts of retinol. You’ll be amazed at how much younger and radiant your skin will look and feel.

A consumer panel test showed that 92% of users preferred this retinol product over other, similar products they've used.

Who is this product for?
Those looking for a more potent product designed to preserve young skin and repair more advanced signs of aging, including: deep wrinkles, fine lines, and brown spots. In addition, Clinical 1% Retinol Treatment will help prevent blemishes and correct red marks from past breakouts.

Sources to support the claims made for the Clinical 1% Retinol Treatment

Journal of Investigative Dermatology, August 2013, ePublication; Journal of Drugs in Dermatology, May 2013, pages 533–540; March 2013, pages S42–S44; and January 2012, online; Pharmaceutical Research, February 2013, pages 538–551; Advances in Skin and Wound Care, May 2013, pages 224–229; Journal of Dermatological Science, April 2012, pages 51–59; Experimental Dermatology, July 2011, pages 572–576; International Journal of Cosmetic Science, February 2011, pages 62–69; British Journal of Dermatology, December 2010, pages 1,157–1,165; Bioscience, American Journal of Clinical Dermatology, Volume 9, 2008, pages 369–381; Biotechnology, and Biochemistry, October 2008, pages 2,589–2,597; and New England Journal of Medicine, May 1993, pages 1,438–1,443.

Key Ingredients: Salix alba extract, dipotassium glycyrrhizate, Arctium lappa, phytosterol, cetyl esters, tetrahexyldecyl ascorbate, retinol, tribehenin, Glycine soja sterols, glycerin, sodium hyaluronate, allantoin, Avena sativa, palmitoyl tetrapeptide-7, lecithin, dimethicone, laurdimonium hydroxypropyl hydrolyzed soy protein, Glycyrrhiza glabra, ceramide NS, palmitoyl hexapeptide-12, tocopheryl acetate

Product Ingredients:

Water, Dimethicone (silicone slip agent), Glycerin (skin-repairing ingredient), Butylene Glycol (slip agent/penetration enhancer), Isononyl Isononanoate (emollient), Castor Isostearate Succinate (skin-conditioning agent), Glyceryl Stearate (emulsifier), C12-15 Alkyl Benzoate (thickener), Dimethicone Crosspolymer (silicone thickener/texture enhancer), PEG-33 (binding agent), Polysorbate 20 (emulsifier), Behenyl Alcohol (fatty alcohol thickener), Retinol (cell-communicating ingredient), Tetrahexyldecyl Ascorbate (vitamin C/antioxidant), Ceramide 2 (skin-repairing ingredient), Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12 (cell-communicating ingredients), Sodium Hyaluronate (skin-repairing ingredient), Dipotassium Glycyrrhizate, Glycyrrhiza Glabra (Licorice) Root Extract, Avena Sativa (Oat) Kernel Extract, Arctium Lappa (Burdock) Root Extract, Salix Alba (Willow) Bark Extract (antioxidant plant extracts/anti-irritants), Glycine Soja (Soybean) Sterols (antioxidant/skin-conditioning agent), Lecithin (cell-communicating ingredient), Allantoin (anti-irritant), Tocopheryl Acetate (vitamin E/antioxidant), Hydrolyzed Soy Protein (antioxidant), Sorbitan Laurate (emulsifier), Acetyl Dipeptide-1 Cetyl Ester (anti-irritant), Disodium EDTA (stabilizer), Hydroxyethylcellulose (thickener), Sodium Hydroxide (pH adjuster), Tribehenin (emollient), Caprylyl Glycol, Ethylhexylglycerin (skin conditioning agents),Pentylene Glycol (slip agent), PEG-100 Stearate (thickener), PEG-75 Shea Butter Glycerides (emollient), PPG-12/SMDI Copolymer (film-forming agent), PEG-10 Phytosterol (fatty acid-based thickener), PEG-8 Dimethicone (silicone-based skin-conditioning agent), PEG-14 (thickener), Pentaerythrityl Tetraisostearate (binding agent), Polymethylsilsesquioxane (silicone-based opacifying agent), Magnesium Aluminum Silicate (slip agent), Arachidyl Glucoside (emulsifier), Sclerotium Gum (thickener) Arachidyl Alcohol (thickener), Benzoic Acid (preservative), Carbomer (gel-based thickener), Phenoxyethanol (preservative).

DIRECTIONS: Limit initial use to three times per week; gradually increase frequency to every other night, then finally each evening as tolerated. Apply a pea-sized amount after cleansing and/or toning. Carefully avoid the lips, eyes and corners of the eyes. Can be used on the perimeter of the orbital bone if desired. Do not apply to eyelids. To minimize irritation, try combining with 2-3 drops of Resist Moisture Renewal Oil Booster.

May be applied at the same time as your AHA or BHA exfoliant, but pay attention to how your skin responds. If you notice signs of sensitivity, apply your AHA or BHA exfoliant in the morning and this treatment at night or reduce frequency of application of Clinical 1% Retinol Treatment.

Note: Some people may experience a delayed sensitized reaction to 1% retinol. Do not assume that if no reaction is seen after a few applications that you can apply this treatment more frequently. Pay close attention to how your skin responds and adjust usage accordingly.

If sensitization occurs (redness, flaking, tenderness, or drying of skin), reduce frequency of use or mix one pump of the Clinical 1% Retinol Treatment with your favorite Paula’s Choice serum or PM moisturizer. If sensitization persists, discontinue use. Protect skin daily with sunscreen rated SPF 25 or greater, or layer sunscreens (moisturizer, foundation with sunscreen, and pressed powder with sunscreen) if they are all rated SPF 15 or greater (and greater is better).

Do not apply this treatment on the same day as facial waxing or sugaring. Doing so may increase the risk of an irritant response.

TIPS AND TROUBLESHOOTING:

  • Can be worn under or over your PM moisturizer.
  • May be combined with any prescription retinoid product, including Renova, Retin-A, Refissa, Differin, Tazorac, or Avita. Discontinue or reduce frequency of use if irritation develops or persists.
  • Despite the many benefits retinol has, there is no single “best” anti-aging ingredient for skin. The retinol in this product is combined with other anti-aging ingredients for optimal results. The antioxidants and skin-repairing ingredients in this formula were chosen for their well-researched track records and history of being able to improve multiple signs of aging. We’ve also included potent anti-irritants to ensure compatibility with sensitive skin.
  • Remember, not everyone’s skin will be able to tolerate a high percentage of retinol, especially if you’re already using a prescription retinoid or other skincare products that contain retinol.

Detailed instructions on how/when to apply your Paula's Choice products can be found in our How to Put Together Your Own Skincare Routine article.

At what point in my skincare routine would I use Clinical 1% Retinol Treatment?

This nighttime treatment is best applied after cleansing and toning. If you use an AHA or BHA exfoliant, apply that first, then follow with Clinical 1% Retinol Treatment. If you use a skin-lightening product that would be applied next, followed by your serum and nighttime moisturizer.

If you are planning to use Clinical 1% Retinol Treatment with a prescription retinoid, apply the prescription retinoid after cleansing, toning, and exfoliating. Follow with Clinical 1% Retinol Treatment and the rest of your skincare routine. Note that combining this product with a prescription retinoid increases the risk of side effects such as dryness, flaking, and sensitivity.

How does Clinical 1% Retinol Treatment differ from the other retinol products Paula’s Choice offers?

The most notable difference is that Clinical 1% Retinol Treatment contains a higher amount of retinol than our other products with retinol. It is formulated for those whose skin can tolerate prescription-strength retinol but want an over-the-counter alternative or whose skin has more advanced signs of sun damage, including deep wrinkles.

The percentage of retinol needed for efficacy is generally between 0.01%–1%, which is quite a range, but further proof of just how powerful retinol is! For more on percentages of retinol in Paula’s Choice products, see our article Which Strength of Retinol Do I Need?

All of these products may be used with Clinical 1% Retinol Treatment or on their own, as each treats skin to a beneficial range of anti-aging ingredients.

Can I use Clinical 1% Retinol Treatment if I am using other Paula’s Choice products that contain retinol?

Yes, though you may wish to alternate rather than layer—this will depend on how your skin responds. You can also apply your usual retinol product (serum or moisturizer) all over your face and neck, then apply Clinical 1% Retinol Treatment to areas showing more advanced signs of aging: Crow’s feet around the eyes, laugh lines, expression lines, and dark spots.

Is Clinical 1% Retinol Treatment suitable for sensitive skin?

Yes, although of course it always depends on how skin reacts. Our fragrance-free formula contains several anti-irritants designed to minimize any discomfort those with sensitive skin may experience from using a stronger retinol treatment; however, if skin is very sensitive it’s best to apply this treatment less often, perhaps twice per week rather than every night.

Is Clinical 1% Retinol Treatment suitable for rosacea-affected skin?

Yes, although of course it always depends on how skin reacts. There’s research showing retinol can help reduce the inflammation that’s an underlying factor in rosacea.

Can I use Clinical 1% Retinol Treatment if I have oily skin and breakouts?

Yes; in fact, the amount of retinol is akin to prescription-strength retinoids which are often prescribed by dermatologists to manage all types of acne. The silky-smooth finish won’t make oily skin look or feel greasy.

How does Clinical 1% Retinol Treatment compare to prescription retinoids?

This product contains retinol, which is weaker than prescription retinoids but, over time, produces comparable anti-aging and anti-acne results. A prescription retinoid may produce faster results, but it does so with the added risk of side effects like redness, flaking, and increased sensitivity.

A product with 1% retinol is more comparable to a prescription retinoid with 0.02 tretinoin (the active ingredient in Renova and Retin-A).

As with most well formulated anti-aging products, consistent use and daily sun protection will produce the best results.

Is it OK to use Clinical 1% Retinol Treatment with a product that contains hydroquinone, such as Resist Dark Spot Eraser?

Yes, this is fine. Apply the Clinical 1% Retinol Treatment first, and follow with the skin-lightening product, either applied to areas of concern or all over the face.

Is it OK to use Clinical 1% Retinol Treatment with an anti-acne product that contains benzoyl peroxide?

Yes. For best results, apply the benzoyl peroxide product to breakout-prone areas, allow to dry, then follow with Clinical 1% Retinol Treatment.

You may have read or heard that retinol and benzoyl peroxide cannot be used together for fear they will adversely affect each other’s stability.  However, what is often missing from these claims is any cited corroborative studies, and with good reason, because the scientific and medical research actually says the two ingredients can complement each other—which is good to know, whether you’re dealing with acne alone or the unwelcome mix of wrinkles plus breakouts! (Cutis 2009 & 2012, Journal of Drugs and Dermatology 2013).

Are there any products I shouldn’t combine with Clinical 1% Retinol Treatment?

No, it can be used with any other skincare products. However, if you’re combining it with more “active” products such as AHAs, BHA, skin-lightening products, anti-acne products, other retinol or prescription retinoid or prescription anti-acne products, it’s important to pay attention to how your skin responds and adjust usage accordingly. You don’t want to tip the scale in favor of irritation!

How soon will I see results?

From the first use, you will see improved skin texture and radiance. Over the next few weeks, these improvements will continue and you will begin to see a reduction in breakouts, red marks from past breakouts, brown spots, deeper wrinkles, and loss of firmness. After three to four months of consistent use along with daily sun protection (every day, no exceptions) you will see dramatically younger-looking skin with a smooth texture and remarkably even skin tone.

Why should I use Clinical 1% Retinol Treatment instead of one of your other retinol products—and why should I use one of those other retinol products instead of Clinical 1% Retinol Treatment?

You should use Clinical 1% Retinol Treatment if you feel your current retinol product isn’t giving you the results you hoped for after several weeks to months of consistent use (along with daily sun protection, a key component of any anti-aging routine). Clinical 1% Retinol Treatment is a more potent product designed to repair more advanced signs of aging.

You should consider using one of our other retinol products if you suspect your skin may react negatively to a stronger retinol product because attempts to use more potent retinol products (including prescription retinoids) haven’t been successful. Even then, you may still want to consider using Clinical 1% Retinol Treatment once or twice weekly, combined with your regular retinol product or used alone.

Is this the strongest retinol product I can buy over-the-counter?

No, there are a few companies selling over-the-counter products with higher amounts of retinol. Although those may seem intriguing, our in-house and external panel testing revealed that amounts of retinol above 1% came with a much higher likelihood of unwanted side effects such as redness, persistent flaking or peeling, and a sunburn-like sensation. Retinol is an active ingredient, and with any such ingredient you never want to tip the scale from benefits to irritation.

Is Clinical 1% Retinol Treatment safe for me to use while pregnant or nursing?

Due to the higher amount of retinol being closer to the strength of prescription retinoids (which are contraindicated for use while pregnant or breast feeding), we advise against such use unless OK’ed by your physician. If your physician does not provide a clear answer, it’s generally best to be cautious and refrain from use until you are no longer pregnant or breast feeding.

If I see great results after the first or second use, is it OK to begin applying Clinical 1% Retinol Treatment every night?

Because potential side effects from a high-strength retinol product may be delayed, we advise you to not apply this product nightly or every other night until you have been using it for 2–4 weeks with no signs of sensitivity (such as flaking, dryness, or redness). This is very important for those who’ve never used a high-strength or prescription retinoid product, as not everyone’s skin can tolerate stronger retinoids—and you never want to tip the scales in favor of irritation.

Remember: Only a pea-sized amount is needed for the entire face and neck. Using more than this per application will not provide better or faster results.

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