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Resist Cellular Defense Daily Moisturizer SPF 25

This lightweight cream hydrates and protects skin from sun damage, reducing the appearance of wrinkles for radiant, even-toned skin.
Item #: 768
  • Anti-Aging, Extra Sensitive Skin, Wrinkles
  • Best for Normal to Dry; Works for All Skin Types
  • Provides mineral-based broad-spectrum sun protection
  • Fortifies skin with potent antioxidants
  • Lightweight, silky-cream texture is gentle, yet effective

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Resist Cellular Defense Daily Moisturizer SPF 25

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What makes this product unique?
This ultra-gentle yet effective formula has a lightweight, silky-cream texture that hydrates and enhances radiance while providing extremely effective mineral-based, broad-spectrum sun protection. It includes potent antioxidants to defend from free radical damage. Used daily, this moisturizer will help reduce the appearance of wrinkles and brown spots, while improving skin tone.

Fragrance-free, colorant-free, and formulated to work beautifully under makeup. 100% Guaranteed.

Who is this product for?
Resist Cellular Defense SPF 25 is specially formulated for normal to dry or very dry skin. It is a gentle mineral sunscreen that is also excellent for sensitive skin. The creamy texture is not ideal for oily or oily areas of combination skin.

Sources to support the claims made for Resist Cellular Defense Daily Moisturizer with SPF 25

Journal of Agricultural and Food Chemistry, January 2011, pages 193–199; Collegium Anthropologicum, September 2010, pages 1,145–1,153; Planta Medica, June 2010, pages 869–875; American Journal of Clinical Dermatology, 2009 Supplement, pages 19–24; Journal of the American Academy of Dermatology, May 2008, pages S149–S154; Pharmazie, January 2008, pages 58-60; International Journal of Pharmaceutics, August 2010, pages 78–83; and October 2007, pages 181–189; Skin Pharmacology and Physiology, November-December 2005, pages 253–262; Cutis, September 2004, pages 32–34; and

Key Ingredients: tocopheryl acetate, squalane, Leontopodium alpinum extract, Buddleja davidii extract, sodium hyaluronate, tocopherol, Glycine soja seed extract, tribehenin, ubiquinone, vitamin E, glycerin, oryzanol

Product Ingredients:

Active Ingredients: Titanium Dioxide 8%. Other Ingredients: Water (Aqua), Cyclopentasiloxane (silicone slip agents), Tribehenin (PEG-20 Esters) (skin conditioning agent/thickener), Stearic Acid (emollients), Glycerin, Caprylyl Methicone, Squalane (emollients), C12-15 Alkyl Benzoate, Glycine Soja (Soybean) Seed Extract (antioxidants), Trimethylsiloxysilicate (silicone slip agents), Sodium Hyaluronate (skin-repairing ingredient), Tocopherol (vitamin E/antioxidants), Tocopheryl Acetate (vitamin E/antioxidants), Ubiquinone (antioxidants), Oryzanol (antioxidants) , Leontopodium Alpinum Extract (antioxidants), Buddleja Davidii Extract (antioxidants), Aloe Barbadensis (Aloe) Leaf Juice (water-binding agent), Diisopropyl Dimer Dilinoleate (emollient), Diisostearyl Dimer Dilinoleate (emollient), Dimethicone/Vinyl Dimethicone Crosspolymer (silicone film-forming agent), Cetyl Alcohol, Polyacrylamide (film-forming agent), Polyhydroxystearic Acid (thickener), Isopropyl Titanium, Triisostearate/Triethoxycaprylylsilane Crosspolymer (polymer-based texture enhancer), Laureth-7 (emulsifier), Thymus Vulgaris (Thyme) Extract (antioxidant), C13-14 Isoparaffin (thickeners), Alumina (thickeners), Sodium Hydroxide (pH adjuster), Xanthan Gum (thickener), Disodium EDTA (chelating agent), Benzyl Alcohol (preservative), Dehydroacetic Acid (preservative).

DIRECTIONS: Use as the last step in your morning skincare routine. Apply liberally to face, eye area, and neck 15 minutes before sun exposure. Use a water-resistant sunscreen if swimming or sweating. Reapply at least every 2 hours if skin is exposed to sun.

Detailed instructions on how/when to apply your Paula's Choice products can be found in our How to Put Together Your Own Skincare Routine article.

Should I reapply Resist Cellular Defense Daily Moisturizer during the day?

For casual wear, meaning less than four hours total time out in the sun, it is not necessary to reapply this moisturizer with sunscreen as you will be protected all day. If you are perspiring or just spending a longer period of time outdoors, it should be reapplied every few hours to maintain the stated level of protection.

How is Resist Cellular Defense Daily Moisturizer SPF 25 different from Skin Recovery Daily Moisturizing Lotion SPF 30?

Although both products provide reliable broad-spectrum sun protection, Skin Recovery Daily Moisturizing Lotion SPF 30 offers a slightly greater amount of sun protection. Both formulas use mineral sunscreen actives and contain antioxidants to help defend skin against signs of aging.

Texture-wise, these two daytime moisturizers with sunscreen are quite similar. Both provide hydration and a silky, radiant finish those with normal to dry skin will appreciate best. Resist Cellular Defense SPF 25 leaves less sheen on skin when compared to Skin Recovery Daily Moisturizing Lotion SPF 30.

Is Resist Cellular Defense Daily Moisturizer SPF 25 the only Paula's Choice moisturizer with sunscreen that provides anti-aging benefits?

Definitely not! Every Paula's Choice daytime moisturizer with sunscreens as well as our "body" sunscreens (which can also be applied to the face) provide broad-spectrum sun protection and contain antioxidants for enhanced defense and antiaging benefits. Resist Cellular Defense SPF 25 contains an antioxidant blend that complements the other Resist products from Paula's Choice, including the Daily Smoothing Treatment and Super Antioxidant Concentrate Serum.

I notice I get a white cast after applying Resist Cellular Defense Daily Moisturizer. Anything I can do to minimize this?

Some people, typically those with medium to tan or olive skin tones, will notice a bit of a white to pale violet cast after applying Resist Cellular Defense Daily Moisturizer SPF 25. This is due to the amount of mineral active (titanium dioxide) this moisturizer with sunscreen contains. If this happens to you, here's what you can do to eliminate the white cast:

Experiment by applying a drop or two of a sheer bronzing gel (Clinique makes a good one) over Resist Cellular Defense Daily Moisturizer. You can also mix a drop or two of the bronzing gel with this daytime moisturizer before applying. The bronze will offset the white cast and should make your skin tone look more natural without losing the anti-aging sun protection this provides. Of course you can also apply a Paula's Choice foundation with sunscreen over Resist Cellular Defense Daily Moisturizer, too.

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