RESIST Intensive Wrinkle-Repair Retinol Serum

Laughing. Squinting. Living. It all leaves its mark. This retinol-rich serum increases collagen, smooths wrinkles, and softens fine lines.
Item #: 771
  • Anti-Aging, Brown Spots, Rosacea, Wrinkles
  • For All Skin Types
  • Supercharged blend of retinol and antioxidants repairs wrinkles and sun damage

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Customer Ratings:

84 out of 100
(Based on 363 Reviews)
Page of 15 Next »
  1. MARY K.
    Reviewed on Wednesday, April 16, 2014
    100 out of 100
    • Rating
      Best / 4
    Everyday Requirement
    • I use this every morning and mix it with my C15 Super Booster. I have used this for the past two months. My skin is glowing. I have the most even, clear, acne free skin ever. The bottle design ensures stability. It’s a great price. I have had no adverse reactions to my skin. I highly recommend this product.

  2. Anonymous
    Reviewed on Tuesday, April 08, 2014
    100 out of 100
    • Rating
      Best / 4
    Your advice for combating sebaceous hyperplasia is excellent!
    • First of all, you are the only skin care company I have found that even addresses this concern. Second, what you recommend works even better than the skin care protocol that my dermatologist suggested. Over the years, I have spent hundreds of dollars on lotions and potions that claim to help improve skin texture and wrinkles.They have all proved disappointing until now. The triple combination of the Resist BHA 9, the Resist Retinol Serum, and the Skin Balancing Pore Reducing Toner is amazing!

  3. Lynne M.
    Reviewed on Tuesday, April 08, 2014
    40 out of 100
    • Rating
      Poor / 4
    Disappointed
    • I'm a fan of all PC products so I was excited to try this. It caused an breakout on both sides of my face and clogged my pores. So disappointed as my skin was looking fabulous with the Resist line and ended up with quite a setback.

    Customer Service Response
    Replied on: Tuesday, April 08, 2014

    Hi Lynne! Wow, we're sorry the RESIST Retinol Serum didn't work out for you! Please contact our Customer Care Team, as they would be happy to help with a refund/exchange, as well as tips to get your complexion back on track.

    —Admin
  4. Paula
    Reviewed on Friday, April 04, 2014
    100 out of 100
    • Rating
      Best / 4
    Love this stuff!
    • I just started using this 3.5 weeks ago. I love it! PC's products are the only retinols that my skin has been able to tolerate. I am already seeing substantial improvement to my skin. I tried a sample first. That's how I found I could tolerate it. If you are unsure, I recommend you do that too. You will probably be pleasantly surprised like me. I am a PC newcomer but will be coming back for more. Thanks!

  5. Yanti
    Reviewed on Saturday, March 29, 2014
    100 out of 100
    • Rating
      Best / 4
    The best serum...EVER!
    • I got a deluxe sample of this end of 2013 from PC Singapore. First time I used it I was skeptical because to me it has "oily" texture. I used it at night and was expecting clogged pores when I wake up in the morning. The truth is, I woke up in the morning with brighter and dewy skin. Love it! Once I finished the deluxe sample bottle, I ordered the full size. Until now, I still use it nightly. Sometimes, when my forehead skin slightly dry, I'll add on Resist Ultra Light serum. Love! Love! Love

  6. lisa w.
    Reviewed on Thursday, March 27, 2014
    100 out of 100
    • Rating
      Best / 4
    Must have
    • I am not faithful to anything EXCEPT FOR THIS. My skin glows with this. I stockpile it

  7. Anna Z
    Reviewed on Monday, March 17, 2014
    100 out of 100
    • Rating
      Best / 4
    Bye-Bye Breakouts, Blemishes and Hyperpigmentation
    • I started using this 7 weeks ago; 3 weeks ago, I started adding 3 drops of C15. Results are slow at first. I started breaking out less and less. It's been five days since I've had a new pimple (yay!). Last week, I noticed a dime-sized patch of post-acne hyperpigmentation had disappeared. I could swear a shallow scar on my cheek has reduced in depth. The mild crepe-iness on my neck is gone. Fwiw, I started using PC Resist 5% AHA 2x daily one week before I started using this serum.

  8. Nancy
    Reviewed on Saturday, March 15, 2014
    40 out of 100
    • Rating
      Poor / 4
    ok
    • while it's ok, I can't say I'd recommend it. I've been using it at night and morning with C boost. Haven't noticed anything except break outs. In spite of that, I'll keep using it until it's empty.

    Customer Service Response
    Replied on: Monday, March 17, 2014

    Hi Nancy! Thank you for sharing your experience, but we're sorry to learn your RESIST Retinol isn't bringing you the results you had hoped.  Breakouts as you have described may indicate that you cannot tolerate the strength of the formula, and we would recommend contacting our Customer Care Team so that they can discuss your skin's response and help with a refund/credit and/or samples of alternative options.

    —Admin
  9. Lori M.
    Reviewed on Monday, March 10, 2014
    100 out of 100
    • Rating
      Best / 4
    Surprisingly effective
    • I don't like the feeling of silicone on my skin, but this stuff is amazing. It sinks in quickly, doesn't feel greasy and is actually really effective in the eye area. If you're not a fan of silicones, don't be afraid to try this!

  10. Rebekah J.
    Reviewed on Saturday, February 22, 2014
    100 out of 100
    • Rating
      Best / 4
    Wonderful so far!
    • I always thought introducing retinol to my skincare would mean super dry skin and tons of heavy moisturizers, but not with this one! I have dry skin and just 1 week of use (combined w/C15 booster) I actually need LESS moisturizer than before! For the first time in years, I have a simple skincare regimen that is yielding results. No more spending thousands of $$ just to be disappointed...PC Resist line is holy grail material and the prices are amazing!

  11. Angie M
    Reviewed on Wednesday, February 19, 2014
    100 out of 100
    • Rating
      Best / 4
    Best ever!
    • I've tried everything. Have struggled with breakouts my whole life and at 35 I was getting very weary of it. It was even harder as I got older battling acne and wrinkles. This serum (along with the barrier repair moisturizer) have been the ONLY thing that has worked for me. My skin is clear and I only need powder and a touch of concealer here and there for my daily foundation routine. The reason it gets 5 stars is because it is amazing at reducing lines and promoting glowing youthful skin!

  12. Kristie o.
    Reviewed on Friday, February 14, 2014
    100 out of 100
    • Rating
      Best / 4
    Love the product
    • I and my mom really love this serum. It's perfect to use for overnight after using BHA liquid. Thanks again for PC staffs' work.

  13. Marina D
    Reviewed on Thursday, February 13, 2014
    80 out of 100
    • Rating
      Good / 4
    Overall a great product
    • I didn't see the results until about a month after first use. I definitely smoothed out my fine lines and added "bounce" to my skin. It goes on very shiny so I was very worried about breaking out like crazy. However, it wasn't an issue (whew!). To make shine history, I applied PC Skin Balancing Invisible Finish Moisture Gel and voila, it's gone.

  14. KELLY Z.
    Reviewed on Wednesday, February 12, 2014
    80 out of 100
    • Rating
      Good / 4
    Not an overnight miracle but...
    • Other reviews state they see a difference overnight which, I'm here to say, isn't true for me (sadly.) But, consistently apply over 4-6 weeks, and you will likely be blown away. Not only does it decrease fine lines, it adds a bounce to skin and evens the tone. It makes it easier to apply makeup, makes your skin have a glow (especially when paired with C15) and smoothes it. My 2014 resolution was to get better skin, and I'm so happy to say I'm on my way with PC products like this one (and BHAs!)

  15. Yanely M
    Reviewed on Thursday, February 06, 2014
    40 out of 100
    • Rating
      Poor / 4
    Wanted to Love it
    • I figured if I bought this retinol serum the vit-c booster, it would go on smoother and plus the retinol would be a plus. But, unfortunately, all I've noticed are breakouts, and since I use this on my neck, I've had breakouts on my neck area, which is very very rare. Now, I'm seeing dry patchy areas, which is also very very rare. The only thing i have changed in my routine is adding this retinol. So, sad to say, it's a no go for me. :(:(

    Customer Service Response
    Replied on: Thursday, February 06, 2014

    Hi there! We're sorry to learn this wasn't a fit for you, and that your experience didn't match those of others.  It is true that not everyone will be able to tolerate potent treatments like the RESIST Intensive Wrinkle-Repair Retinol. Please contact our Customer Care for assistance in a return or exchange. 

    —Admin
  16. Barbara R.
    Reviewed on Sunday, February 02, 2014
    100 out of 100
    • Rating
      Best / 4
    Love this product!
    • I have really noticed an improvement on my skin. Fine lines and spots are disappearing. My friend also uses this and her skin is looking beautiful!!

  17. Alicia M.
    Reviewed on Saturday, February 01, 2014
    100 out of 100
    • Rating
      Best / 4
    A great daytime Retinol
    • I use Retin-A at night, and due to some changes in my skin (long story), I was looking to add a daytime Retinol product to my routine. I started ROC products during the day, and they did okay, but I felt like there had to be something better out there. I was right! Paula's Retinol serum saved the day! Adding this product to my daytime routine singlehandedly made the difference to bring back my skin health and glow. Thank you Paula!

  18. Mary Lynn
    Reviewed on Monday, January 27, 2014
    100 out of 100
    • Rating
      Best / 4
    Smooths and no bad reaction
    • I've tried for years to use prescription retinol but I always look like my face has dandruff regardless of the strength This Retinol just makes my skin smooth, less creased and thicker. It feels great and is much smoother; not too much makeup needed. I'm 64 and this has made my skin nicer than it has been in years. (Added the C-15 and it's even better.).

  19. marcia s.
    Reviewed on Wednesday, January 22, 2014
    100 out of 100
    • Rating
      Best / 4
    Love this product!
    • I have been using this product around my eyes for the last 2 weeks. I have one eye that has more lines under it than the other. This is the first product that really seems to be making a difference in the appearance of those lines. I have tried a multitude of other "eye creams" and had little success with the outcome, especially given the price of some of those products. I have only been using Paula's Choice Resist skin products for a few months, and am extremely happy with the look of my skin.

  20. CT
    Reviewed on Monday, January 20, 2014
    100 out of 100
    • Rating
      Best / 4
    Feels great on your skin
    • I just bought this product, so it's too soon to see any results. BUT, I absolutely LOVE the way this serum feels on my face..silkly texture and it dries fast! I prefer to put on my moisturizer first, then top with this serum and allow it to dry. So far so good!!

  21. Meahlyn D.
    Reviewed on Monday, January 20, 2014
    100 out of 100
    • Rating
      Best / 4
    Pleasantly surprised
    • I received a generous deluxe sized sample from a contest and used it for at least two months. After the first month, I didn't notice much of a difference in my dark post acne scars and blemishes. However, by the second month and a little after, the darks spots were significantly reduced. With continued use, I believe this product has and will change my life. Thanks Paula's Choice!

  22. nancy
    Reviewed on Sunday, January 19, 2014
    60 out of 100
    • Rating
      Neutral / 4
    Jury still out.
    • I've been using it for a few weeks now. I know that I like the way it feels going on. I use it with the C Boost. I'm going to keep using and report back in a month.

  23. Jackie B
    Reviewed on Thursday, January 16, 2014
    100 out of 100
    • Rating
      Best / 4
    Never without it...
    • Used this daily for maybe 2 years & wouldn't let my 62 year skin go without it . Truly makes a difference so I'm seldom without a spare watching always for Paula's specials. Is their shipping warp speed or what?!

  24. Kristy
    Reviewed on Tuesday, January 14, 2014
    40 out of 100
    • Rating
      Poor / 4
    Not quite what I expected....
    • I ordered based on the good reviews as some people that I know absolutely swear by Paula's Choice products. I ordered this along with the vit-c serum and not sure if this blend is too harsh or what, but I had a breakout which is extremely rare. This was the only thing I changed in my current skincare routine. I have since been ordering samples of everything trying to see what works and what doesn't. Dissapointed as this was my very first order and an expensive one at that.

    Customer Service Response
    Replied on: Friday, January 17, 2014

    Thank you for sharing your review, and we're sorry this wasn't a fit for you! Be sure to contact our Customer Care for assistance with a refund or exchange, custserv@paulaschoice.com.

    —Admin
  25. Anna F.
    Reviewed on Monday, January 13, 2014
    40 out of 100
    • Rating
      Poor / 4
    Great product
    • Love this! Since I started using this a couple of weeks ago I have noticed a big improvement, so much so that I ordered another bottle. Unfortunately, the first bottle stopped working, I just started the 2nd one and hope it continues to work because i find it was really expensive and I can't afford to reorder a 3rd time if it doesn't work.

Page of 15 Next »

What makes this product unique?
Paula's Choice RESIST Intensive Wrinkle-Repair Retinol Serum is an exclusive formula that utilizes a proprietary blend of highly stabilized retinol, potent antioxidants, and skin-repairing ingredients. Its soothing, silky texture goes to work immediately to help skin of any age look and act younger. Anti-irritants reduce redness and soothe sensitive skin, and the serum helps fade red marks from past breakouts. With ongoing use, you will see fewer wrinkles, smoother skin, and improved skin tone.

This product is 100% fragrance- and colorant-free.

Who is this product for?
Anyone concerned with improving the appearance of aging skin and helping sun-damaged skin repair itself so it functions in a younger, healthier manner. Ideal for use with Paula's Choice RESIST line of anti-aging products. May be alternated with our best-selling RESIST Super Antioxidant Concentrate Serum.

Sources to support the claims made for RESIST Intensive Wrinkle-Repair Retinol Serum

Duodecim, Volume 128, Issue 22, 2012, pages 2,327–2,335; Journal of the European Academy of Dermatology and Venereology, September 2011, ePublication; Experimental Dermatology, July 2011, pages 572–576; Journal of Drugs in Dermatology, June 2011, pages 614–620; Fitoterapia, March 2011, pages 208–211; Lipids, September 2010, pages 833–841; Oxidative Medicine and Cellular Longevity, January-February 2010, pages 35–43; The Journal of Dermatological Treatment, May 2009, pages 276–281; Journal of the Indian Medical Association, April 2009, pages 219–222; American Journal of Clinical Dermatology, June 2008, pages 369–381; International Journal of Cosmetic Science, June 2008, pages 175–182; Journal of Dermatological Science, May 2008, pages 99–107; Archives of Dermatology, May 2007, pages 606–612; and Clinical Interventions in Aging, April 2006, pages 327-348.

Key Ingredients: retinol, caprylic/capric triglyceride, squalane, licorice extract, cell-communicating ingredients, Avena sativa, Laminaria ochroleuca extract, bisabolol, lecithin, palm oil, vitamin C, anti-irritant, antioxidant, vitamin E, kelp extract

Product Ingredients:

Cyclopentasiloxane, Dimethiconol (silicone slip agents/suspending agents), Neopentyl Glycol Diheptanoate (skin-conditioning agent), Dicaprylyl Carbonate (emollient), Caprylic/Capric Triglyceride (skin-repairing ingredient), Phenyl Trimethicone (silicone slip agent), Squalane (emollient), Bisabolol (anti-irritant), Tetrahexyldecyl Ascorbate (stabilized vitamin C/antioxidant), Retinol (cell-communicating ingredient/antioxidant), Tocotrienols (vitamin E-based antioxidant), Tocopherol (vitamin E/antioxidant), Lecithin (cell-communicating ingredient), Laminaria Ochroleuca (Kelp) Extract (anti-irritant), Avena Sativa (Oat) Kernel Oil (anti-irritant), Elaeis Guineensis (Palm) Oil (skin-repairing ingredient), Stearyl Glycyrrhetinate (licorice-derived anti-irritant), Hexylene Glycol (slip agent), Caprylyl Glycol (emollient), Ethylhexylglycerin (skin-conditioning agent), Phenoxyethanol (preservative).

DIRECTIONS: Apply in the evening after cleansing, toning, and exfoliating. Smooth a few drops onto skin before or after moisturizing. Perfect for use around the eyes. May be alternated with Paula’s Choice RESIST Super Antioxidant Concentrate Serum.

Detailed instructions on how/when to apply your Paula's Choice products can be found in our How to Put Together Your Own Skin-Care Routine article.

How does RESIST Intensive Wrinkle-Repair Retinol Serum differ from the other Antioxidant Concentrates that Paula's Choice offers?

The most notable difference is that RESIST Intensive Wrinkle-Repair Retinol Serum contains a higher amount of retinol than our Skin Recovery and Skin Balancing serums with retinol. The RESIST Super Antioxidant Concentrate Serum does not contain retinol and as such is an excellent serum to alternate with the Intensive Wrinkle-Repair Retinol Serum.  Both of the RESIST serums were designed for all skin types, whereas Skin Recovery Super Antioxidant Concentrate Serum is best for normal to very dry skin and Skin Balancing Super Antioxidant Mattifying Concentrate is best for normal to oily or combination skin.

Every Paula's Choice Super Antioxidant Concentrate Serum is silicone-based and contains an effective blend of antioxidants, skin-repairing ingredients, and cell-communicating ingredients to restore skin and significantly reduce wrinkles, increase collagen production, and improve skin color.

Which Paula's Choice serum should I use?

All skin types can use any of our serums, but there are some formulary distinctions that make certain Paula's Choice serums preferred for specific skin types. Here's how they break down:

  • RESIST Super Antioxidant Concentrate Serum and RESIST Intensive Wrinkle Repair Retinol Serum can be used by all skin types, including sensitive skin.
  • Skin Recovery Super Antioxidant Concentrate Serum is best for normal to very dry skin because it contains plant oils.
  • Skin Balancing Super Antioxidant Concentrate is best for normal to oily or combination skin because it has the lightest texture and weightless finish.
  • RESIST Super Antioxidant Concentrate Serum is one of two Paula’s Choice serums that does not contain retinol. It’s the natural choice for anyone whose skin cannot tolerate retinol.
  • RESIST Ultra-Light Super Antioxidant Concentrate Serum has the lightest texture of all the RESIST serums and is our only water-based (rather than silicone-based) serum. It does not contain retinol, so is recommended for those whose skin cannot tolerate this ingredient (or it may be used with one of our retinol serums).

Is RESIST Intensive Wrinkle-Repair Retinol Serum better than the other Paula's Choice serums?

Not better, just different. Think of it like broccoli and carrots: both are good for you but provide different nutritional benefits your body needs to be healthy. RESIST Intensive Wrinkle-Repair Retinol Serum was formulated with a greater amount of retinol to provide a higher degree of wrinkle repair—but all Paula's Choice serums contain an array of ingredients proven to help repair wrinkles and other signs of aging.

Can I use two Paula's Choice products with retinol, such as RESIST Barrier Repair Moisturizer with RESIST Intensive Wrinkle-Repair Retinol Serum?

Yes, this is fine; however, if you noticed that applying such products at the same time causes signs of irritation (such as redness or flaking) it would be best to apply one in the morning and the other at night, or consider switching to RESIST Super Antioxidant Concentrate Serum, which is retinol-free.

Can I use RESIST Intensive Wrinkle-Repair Retinol Serum with my prescription retinoid product (examples: Renova, Retin-A, generic tretinoin).

Yes, but generally speaking, you don't necessarily need to use retinol and a prescription retinoid. Many will do fine with one or the other, or you can apply the prescription retinoid at night and apply the retinol product during the day, always being sure to protect your skin with a product rated SPF 15 or greater. Keep in mind that using multiple retinoid products increases the risk of irritation, which is never the goal. With retinoids, more is not automatically better!

Can I apply RESIST Intensive Wrinkle-Repair Retinol Serum with a product medicated with benzoyl peroxide?

Yes. For best results, apply the benzoyl peroxide product to breakout-prone areas, allow to dry, then follow with RESIST Intensive Wrinkle-Repair Retinol Serum. Note that benzoyl peroxide should not be applied at the same time as the prescription retinoid tretinoin, as it renders this active ingredient ineffective. It does not appear to have this same effect on retinol.

What is the percentage of retinol in RESIST Intensive Wrinkle-Repair Retinol Serum?

Paula's Choice does not reveal the exact percentage of ingredients in any of our products except in the case of over-the-counter drug ingredients such as sunscreen actives and for our exfoliants. In these instances, knowing the exact percentage (or range) is critical as it impacts efficacy.

With retinol, amounts from 0.01–1% have proven to be effective, though higher amounts are known to increase the risk of side effects such as redness, sensitivity, and flaking. RESIST Intensive Wrinkle-Repair Retinol Serum contains an amount of retinol that's greater than our other serums with retinol. All Paula's Choice serums with retinol are formulated with stabilized retinol within the range of what research has shown to be effective for reducing wrinkles, improving skin tone, and building collagen.

Can I layer Paula's Choice serums? Do I need to do this?

Yes, you can and it does not matter which serum is applied first. Experiment to see which order of serum application works best for you. Although it's fine to layer our serums, ultimately you do not need to do this because every Paula's Choice serum treats skin to an array of brilliant ingredients. Because layering two serums plus your daytime moisturizer may feel too heavy under makeup, we recommend those who wish to layer our serums do so at night.

What makes RESIST Intensive Wrinkle-Repair Retinol Serum better than other retinol treatments?

RESIST Intensive Wrinkle-Repair Retinol Serum holds several advantages over other serums with retinol:

  • In addition to its targeted retinol formula, this serum also treats skin to a range of antioxidants, repairing ingredients, and anti-irritants. Each of these ingredients has published research showing how they improve aging skin.
  • The amount of retinol in this serum was expertly calibrated to ensure maximum efficacy without irritation. You're getting all of the benefits of retinol without bothersome side effects such as redness or flaking.
  • The chemist Paula chose to formulate this serum is a retinol expert who made sure every element of this targeted treatment was designed to improve wrinkles and signs of aging without tipping the scale toward irritation.
  • This retinol serum is packaged to ensure the efficacy and stability of the formula. The retinol itself is carefully handled and never exposed to degrading light or oxygen at any time during manufacturing.  The RESIST Intensive Wrinkle-Repair Retinol Serum requires specially designed packaging to keep this amount of retinol stable (droppers, pads or tubes would compromise the retinol's effectiveness). That means the serum you receive can deliver the full, pure potency of retinol.
  • You can rely on Paula and her Product Development team to provide the most advanced formulas at reasonable prices!

At what point after my laser and/or peel procedure can I begin using my serum again?

First, we urge you to follow the post-procedure instructions your doctor or nurse provided. If nothing was mentioned about when to resume use of a serum, please contact the doctor's office where you had the procedure done. Otherwise, our general advice is to begin using your serum again as soon as possible. All of our serums contain skin-repairing, anti-inflammatory, and replenishing ingredients that calm reddened skin and help enhance the healing process. Make sure you're also protecting your "new" skin every day with a product rated SPF 15 or greater.

Is RESIST Intensive Wrinkle-Repair Retinol Serum suitable for those with rosacea?

Yes. Research has shown that retinol can reduce inflammation that leads to symptoms of rosacea. The other antioxidants and soothing agents in this serum will help calm redness and soothe skin as they deliver anti-aging benefits.

I keep depressing the pump, but no product is coming out.

This product is packaged in an airless pump dispenser which utilizes a vacuum system to dispense and keep the contents fresh. Airless packaging helps to keep air and contaminates out of the product, which enhances the formula's stability and effectiveness.

When using your product for the first time, you may need to “prime” the dispenser. To prime, simply pump the dispenser slowly about 10-15 times. If the dispenser stops working at any time, simply repeat the "priming" step. Do not attempt to dismantle the package.

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