CLINICAL Ceramide-Enriched Firming Moisturizer
Based on 168 reviews
Fortify skin’s protective barrier with concentrated ceramides to visibly smooth wrinkles, renew a firmer feel, and enhance moisture balance for plumper skin.

CLINICAL Ceramide-Enriched Firming Moisturizer

Based on 168 reviews
Visibly smooth wrinkles, renew a firmer feel and enhance moisture balance with a concentrated blend of ceramides plus a potent blend of vitamin c and retinol that plumps skin and fortifies skin’s protective barrier.
  • Strengthens the building blocks of healthy skin
  • Replenishing lipids deliver a supple look & feel
  • Creamy-smooth lotion intensely hydrates
  • Use daily to keep skin firm & resilient
Skin Types:
All Skin Types
    1.7 oz
Why is it different?
An unprecedented combination of ceramides, plus retinol and vitamin C, in one moisturizer for dramatically younger-looking skin. This is the first formulation with our CollagenSupport Complex, which acts as a binding agent to keep the outer layers of skin hydrated and resilient.
What does it do?
As we age, the ceramides that keep skin healthy and strong decline. This formula steps in to give skin back five essential ceramides to restore firmer-looking, supple-feeling skin. Retinol and vitamin C further help skin to regain its vitality, while soothing emollients soften the appearance of wrinkles.
How to use
At night, use as the last step in your skincare routine. For daytime, follow with a broad-spectrum sunscreen rated SPF 30 or greater.
Note: This anti-aging moisturizer contains a stronger, highly focused mix of anti-aging ingredients, including several forms of vitamin C and retinol. For best results, do not apply at the same time as other vitamin C or retinol products until you see how your skin responds. If you experience signs of sensitivity, reduce frequency of use.
Show details
Clinical Moisturizer.

Nutrients, August 2017, ePublication

International Journal of Cosmetic Science, May 2017, pages 824-834

Journal of Cosmetic Dermatology, December 2016, pages 549-558

Skin Pharmacology and Physiology, June 2015, pages 1,501-1,509

Journal of Investigative Dermatology, May-June 2016, issue 1—3, pages 279-287

Journal of the American Academy of Dermatology, May 2014, pages AB26; and November 2012, pages 1,103–1,024

Journal of Ethnopharmacology, November 2013, pages 395-420

Indian Dermatology Online Journal, April-June 2013 pages 143-146

Dermatologic Therapy, May 2007, pages 606–612

Clinical Interventions in Aging, 2006, pages 327–348

Product Ingredients Water (Aqua), Sodium Ascorbyl Phosphate (vitamin C/antioxidant), Cetyl Alcohol (texture enhancer, Ascorbyl Glucoside (vitamin C/antioxidant), Neopentyl Glycol Diheptanoate (texture enhancer), Potassium Cetyl Phosphate (emulsifier), Glyceryl Stearate (emollient), PEG-100 Stearate (texture enhancer), Glycerin (skin-replenishing), PEG-12 Glyceryl Dimyristate (hydration), Bis-Diglyceryl Polyacyladipate-2 (emollient), Dimethicone (emollient), Glyceryl Ascorbate, Tetrahexyldecyl Ascorbate (vitamin C/antioxidants), Retinol (vitamin A/skin-restoring), Ceramide NP, Ceramide NS, Ceramide AP, Ceramide EOP, Ceramide EOS, Cholesterol, Caprooyl Phytosphingosine, Caprooyl Sphingosine (skin-replenishing), Squalane (emollient), Punica Granatum Fruit Extract (pomegranate/antioxidant), Pongamia Glabra Seed Oil (non-fragrant plant oil/antioxidant), Glycyrrhiza Glabra (Licorice) Root Extract (skin-soothing), Vitis Vinifera (Grape) Seed Extract (antioxidant), Tocopheryl Acetate (vitamin E/antioxidant), Carnosine (skin-restoring), Panthenol (hydration), Sodium PCA (skin-replenishing), Butylene Glycol (hydration), Sodium Citrate (pH adjuster), Ceteareth-25 (texture enhancer), Polysorbate 20 (emulsifier), Ethylhexyl Stearate (emollient), Sodium Hydroxide (pH adjuster), Trideceth-6 (emulsifier), Propyl Gallate (antioxidant),Ammonium Acryloyldimethyltaurate/VP Copolymer, Sodium Polyacrylate (film-forming agents), Behenic Acid (texture enhancer), Disodium EDTA (chelating agent), Phenoxyethanol, Caprylyl Glycol, Chlorphenesin (preservatives).

Ratings & Reviews

Great Firming Mousturizer


I use it for about a month and I can see my skin more firm, give a try, I have oily skin and for that reason I don't like to much the consistency but anyway does exactly what it says.


Miami FL


love it


like the lotion and texture of this over the Intensive Wrinkle Repair serum. Lite texture works well with layering with other products. No adverse problems with retinol content. Please don't change the formulation.




Love this cream


I read most of the good and bad reviews. To the people whose product didn't last, keep the box and store the product in the box upside down. You should get about 3 months use. I agree that it isn't the most moisturizing cream, but for my combination skin I'm happy! I mix it with a pump of Hyaluronic booster and that's enough for summer, for winter I use a pump of Resist Barrier Repair mixed in. Mind you, my skin is used to retinol and that took a month or so. My 59 year old skin is firming up and plump, but I have used it every night since it came out. Love it.




Wonderful results


I don't normally write reviews, but I LOVE this product! I have been using it since it came out. I am 70 yrs. old and have used Paula's Choice skin care since it first arrived on the scene, so my skin is in great condition to begin with. But I am 70, so there are signs of age. Since I started using the Clinical Ceramide-Enriched Firming Moisturizer, I have definitely noticed that my skin is firmer. It works just as stated. Now I can't wait to see how the Ceramide Eye Cream works!


Sellersville, PA


Love it


Ceramide moisturizing cream is the best!!! It has completed my beauty regimen. I would like to try the eye cream; need to save some money to get it. Try the cream.... you have nothing to lose!!


Albany, IN


Amazing! I'm in love!


I have been using this every night since it first became available and now I'm using it morning (with spf) and night. My skin is simply fabulous since my first week of use. And it seems to just keep getting better. People are always complimenting me on my beautiful skin. At 57 years old compliments are welcome. I can state with honesty that I absolutely attribute my smooth and supple skin to this moisturizer, the Clinical Retinol and hyaluronic acid serum/booster.


Beeton, Ontario, Canada


What an amazing product


I've never had one product do so much in such a short time for my skin. It absolutely firms. I also have rosacea and this did not aggravate it. Thank you


St Louis


Revising my previous review


When I tried this product originally about 5months ago it irritated my face and neck terribly. I ended up at that time using hydrocortisone for 10 days trying to heal my skin. So I put the product in the drawer and forgot about it. I had run out of my usual PC moisturizer(skin balancing ) so I tried the ceramide cream again but with no other Retinol product and it was fine! So now I'm using the Retinol only at night and the ceramide during the day along with spf. And now there's peace in the valley again ;)






I absolutely love this product! It has not irritated my skin at all. The first couple times I used it I felt a little tingly sensation but after that it felt normal. I use it about 3 times a week at night and the results are amazing. My 47 yr old skin feels so much firmer and I've received a lot of compliments. I'm sad when I see bad reviews for this product, I do understand that everyone's skin reacts differently but I really don't want this to ever be discontinued and I want other women to benefit from this awesome product. Again, it's amazing!

Colorado Cathy



Just ordered a second so I don't run out.


So incrededibly pleased with the results having used this moisturiser for a week now. After some minor stinging on my cheeks when I first used it, my skin has adapted to it with no problems. I apply it at night after my exfoliant, and in the morning my skin is soft and well hydrated. I consider this now to be a permanent addition to my skin care regimen, and all my products are from Paula's Choice. There simply is no other skin care line for me. Many thanks to Paula Begoun, for the tireless research she puts into the formulation of her superior products.


Burton, NB



3.7 168