CLINICAL Ceramide-Enriched Firming Moisturizer
Based on 154 reviews
Fortify skin’s protective barrier with concentrated ceramides to visibly smooth wrinkles, renew a firmer feel, and enhance moisture balance for plumper skin.

CLINICAL Ceramide-Enriched Firming Moisturizer

Based on 154 reviews
Visibly smooth wrinkles, renew a firmer feel and enhance moisture balance with a concentrated blend of ceramides plus a potent blend of vitamin c and retinol that plumps skin and fortifies skin’s protective barrier.
  • Strengthens the building blocks of healthy skin
  • Replenishing lipids deliver a supple look & feel
  • Creamy-smooth lotion intensely hydrates
  • Use daily to keep skin firm & resilient
Skin Types:
All Skin Types


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    1.7 oz
Why is it different?
An unprecedented combination of ceramides, plus retinol and vitamin C, in one moisturizer for dramatically younger-looking skin. This is the first formulation with our CollagenSupport Complex, which acts as a binding agent to keep the outer layers of skin hydrated and resilient.
What does it do?
As we age, the ceramides that keep skin healthy and strong decline. This formula steps in to give skin back five essential ceramides to restore firmer-looking, supple-feeling skin. Retinol and vitamin C further help skin to regain its vitality, while soothing emollients soften the appearance of wrinkles.
How to use
At night, use as the last step in your skincare routine. For daytime, follow with a broad-spectrum sunscreen rated SPF 30 or greater.
Note: This anti-aging moisturizer contains a stronger, highly focused mix of anti-aging ingredients, including several forms of vitamin C and retinol. For best results, do not apply at the same time as other vitamin C or retinol products until you see how your skin responds. If you experience signs of sensitivity, reduce frequency of use.
Show details
Clinical Moisturizer.

Nutrients, August 2017, ePublication

International Journal of Cosmetic Science, May 2017, pages 824-834

Journal of Cosmetic Dermatology, December 2016, pages 549-558

Skin Pharmacology and Physiology, June 2015, pages 1,501-1,509

Journal of Investigative Dermatology, May-June 2016, issue 1—3, pages 279-287

Journal of the American Academy of Dermatology, May 2014, pages AB26; and November 2012, pages 1,103–1,024

Journal of Ethnopharmacology, November 2013, pages 395-420

Indian Dermatology Online Journal, April-June 2013 pages 143-146

Dermatologic Therapy, May 2007, pages 606–612

Clinical Interventions in Aging, 2006, pages 327–348

Product Ingredients Water (Aqua), Sodium Ascorbyl Phosphate (vitamin C/antioxidant), Cetyl Alcohol (texture enhancer, Ascorbyl Glucoside (vitamin C/antioxidant), Neopentyl Glycol Diheptanoate (texture enhancer), Potassium Cetyl Phosphate (emulsifier), Glyceryl Stearate (emollient), PEG-100 Stearate (texture enhancer), Glycerin (skin-replenishing), PEG-12 Glyceryl Dimyristate (hydration), Bis-Diglyceryl Polyacyladipate-2 (emollient), Dimethicone (emollient), Glyceryl Ascorbate, Tetrahexyldecyl Ascorbate (vitamin C/antioxidants), Retinol (vitamin A/skin-restoring), Ceramide NP, Ceramide NS, Ceramide AP, Ceramide EOP, Ceramide EOS, Cholesterol, Caprooyl Phytosphingosine, Caprooyl Sphingosine (skin-replenishing), Squalane (emollient), Punica Granatum Fruit Extract (pomegranate/antioxidant), Pongamia Glabra Seed Oil (non-fragrant plant oil/antioxidant), Glycyrrhiza Glabra (Licorice) Root Extract (skin-soothing), Vitis Vinifera (Grape) Seed Extract (antioxidant), Tocopheryl Acetate (vitamin E/antioxidant), Carnosine (skin-restoring), Panthenol (hydration), Sodium PCA (skin-replenishing), Butylene Glycol (hydration), Sodium Citrate (pH adjuster), Ceteareth-25 (texture enhancer), Polysorbate 20 (emulsifier), Ethylhexyl Stearate (emollient), Sodium Hydroxide (pH adjuster), Trideceth-6 (emulsifier), Propyl Gallate (antioxidant),Ammonium Acryloyldimethyltaurate/VP Copolymer, Sodium Polyacrylate (film-forming agents), Behenic Acid (texture enhancer), Disodium EDTA (chelating agent), Phenoxyethanol, Caprylyl Glycol, Chlorphenesin (preservatives).

Ratings & Reviews

What an amazing product


I've never had one product do so much in such a short time for my skin. It absolutely firms. I also have rosacea and this did not aggravate it. Thank you


St Louis


Revising my previous review


When I tried this product originally about 5months ago it irritated my face and neck terribly. I ended up at that time using hydrocortisone for 10 days trying to heal my skin. So I put the product in the drawer and forgot about it. I had run out of my usual PC moisturizer(skin balancing ) so I tried the ceramide cream again but with no other Retinol product and it was fine! So now I'm using the Retinol only at night and the ceramide during the day along with spf. And now there's peace in the valley again ;)






I absolutely love this product! It has not irritated my skin at all. The first couple times I used it I felt a little tingly sensation but after that it felt normal. I use it about 3 times a week at night and the results are amazing. My 47 yr old skin feels so much firmer and I've received a lot of compliments. I'm sad when I see bad reviews for this product, I do understand that everyone's skin reacts differently but I really don't want this to ever be discontinued and I want other women to benefit from this awesome product. Again, it's amazing!

Colorado Cathy



Just ordered a second so I don't run out.


So incrededibly pleased with the results having used this moisturiser for a week now. After some minor stinging on my cheeks when I first used it, my skin has adapted to it with no problems. I apply it at night after my exfoliant, and in the morning my skin is soft and well hydrated. I consider this now to be a permanent addition to my skin care regimen, and all my products are from Paula's Choice. There simply is no other skin care line for me. Many thanks to Paula Begoun, for the tireless research she puts into the formulation of her superior products.


Burton, NB


My skin looks amazing


I've been using a hideously expensive line from my dermatologist post-laser treatment, and can't wait for all of those products to be used up so I can switch back to PC completely. This wonder cream has so many great skin care ingredients I can ditch the expensive retinol and vitamin C I've been using. On another note, I occasionally see people here complaining about price increases in PC products. That's just silly. Compared to high-end store brands, PC is still a bargain, plus you know that you're getting great products.


British Columbia


Best Product I've had so far!


I've been a customer almost from the beginning and I have to say, this is the most outstanding product I've tried (I've tried a lot of Paula's Choice). My skin is (40+) combination with a little bit of acne every now a then. I've used this everyday since I received it. It's now been about 2 weeks or so and no problems what so ever. I consider myself to have sensitive skin, I can't use retinol on my face. Even though this product has retinol in it, it's been perfectly fine. I noticed results within just a few days. My skin is more even, barely any breakouts and it just feels great when I apply this. I use it after I apply the bha liquid. I have many other serums/boosters from PC but I feel like I don't even need to use them. This product has had faster and more noticeable results than anything I've used. I will absolutely purchase again!


Ottawa, Canada


Improved Skin Texture


More than any other product - including the AHA and BHA exfoliants - this product has completely re-texturized my skin. I dont have acne, but the surface of my skin doesnt feel completely smooth, either. This product makes my skin look and feel so much smoother, it is really remarkable. It has replaced many other products, including serums, because with just this one product i can improve redness, clear up the skin so its nice and smooth, and fight aging. Yes, it is expensive. But since it takes the place of other products, it is worth it to consolidate and get one good product that i know will work well.


Santa Clarita, CA




Wow Paula! you really hit the proverbial nail on the head when creating the "magic Peptide" Booster solution along with your absolutely amazing Clinical Ceramide-Enriched Firming Moisturizer! I bought these two beauties at the same time and couldn't have been more surprised and pleased with the results is such a short period of time. The industry has been long over due for a good product with ceramides because of its abilities to stimulate collagen in the skin. I'm not easy to please nor do I make a habit of submitting glowing reviews but for knock out products like these it couldn't be more deserving! I'm re-ordering today and placing them on auto ship every three month's. Nice work !!!!


Cardiff, CA.


Best moisturizer I have tried!


I was a little hesitant to buy this after reading the reviews, but am so glad I did! I am in my late 30's with oily, dehydrated flaky skin and starting to get some dark spots from years of tanning in my 20's. This has made my skin more plump and even toned, no more flaky skin and the little makeup I wear goes on so smooth. I've only been using it at night for the last month so I haven't noticed a reduction in the few wrinkles I have around my eyes, but my skin just looks better. I highly recommend.




trial and error


I have tried many different anti-aging moisturizers and BINGO!!! This supersedes anything I have put on my face. I use this product mainly at night but also in the morning around my eyes and forehead areas only. The first day I used it in the AM, I thought "holy cow!!!" the skin pulling I felt was honestly something I've never felt. It is smoothing and moisturizing as well! Very satisfied. My sister who I haven't for about a year since she moved told me "your skin looks amazing!". Thank you Paula and staff for developing such a great and effective product!





3.7 154