RESIST Intensive Wrinkle-Repair Retinol Serum
Based on 567 reviews
This extravagantly silky serum blends pure retinol and potent antioxidants to help impart firmer-feeling skin, smooth and soften fine lines and wrinkles, and provide hydration so skin of any age can look radiant and revitalized.

RESIST Intensive Wrinkle-Repair Retinol Serum

Based on 567 reviews
This extravagantly silky serum blends pure retinol and potent antioxidants to help impart firmer-feeling skin, smooth and soften fine lines and wrinkles, and provide hydration so skin of any age can look radiant and revitalized.
  • Stabilized retinol improves the appearance of wrinkles
  • Vitamin C helps brighten and replenish skin
  • Silky serum leaves skin soft and smooth
  • Use twice daily after cleansing, toning & exfoliating
Skin Types:
All Skin Types
Wrinkles, Anti-Aging


    1 oz
    Travel Size...
Why is it different?
RESIST Intensive Wrinkle-Repair Retinol Serum is an exclusive formula that contains a unique blend of highly stabilized retinol, vitamin-derived antioxidants, and soothing anti-aging plant extracts, all in packaging that keeps the retinol and other beneficial ingredients stable and effective.
What does it do?
Delivers pure retinol to skin in a silky-smooth serum fluid infused with potent antioxidants and superior skin-replenishing and -hydrating ingredients. This unique combination addresses the appearance of wrinkles, improves the feel of firmness, uneven skin tone, and red marks, and leaves skin looking perfectly radiant.
How to use

Smooth a few drops onto face, neck and eye area before moisturizing (or use alone). For optimal results, use AM and PM. For daytime, follow with a broad-spectrum sunscreen rated SPF 30 or greater.

Show details

Indian Journal of Dermatology, Venereology, March-April 2012, issue 2, pages 142-5

Current Pharmaceutical Biotechnology, 2014, issue 2, pages 173-81

Indian Journal of Dermatology, May-June 2016, issue 1, pages 279-287

Marine Drugs, January 2013, issue 1, pages 146–164

International Journal of Toxicology, 2001, volume 20, supplement 1, pages 21-45

Pharmacology and Physiology, March-April 2005, issue 2, pages 81-7

Indian Journal of Dermatology, May-June 2016, volume 6, issue 1, 3 pages 279-287

Indian Dermatology Online Journal, April-June 2013, volume 4, issue 2, pages 143-146

Dermatologic Therapy, September-October 2007, volume 20, issue 5, pages 314-21

Product Ingredients

Cyclopentasiloxane (hydration), Dimethiconol (hydration/texture-enhancing), Neopentyl Glycol Diheptanoate (emollient), Dicaprylyl Carbonate (emollient), Caprylic/Capric Triglyceride (hydration/skin replenishing), Phenyl Trimethicone (hydration), Squalane (emollient), Bisabolol (skin-soothing), Tetrahexyldecyl Ascorbate (vitamin C/antioxidant), Retinol (skin-restoring/antioxidant), Tocotrienols (vitamin E-based antioxidant), Tocopherol (vitamin E/antioxidant), Lecithin (skin-restoring), Laminaria Ochroleuca Extract (kelp extract/skin-soothing), Avena Sativa Kernel Oil (oat extract/skin-soothing), Elaeis Guineensis Oil (palm oil/skin replenishing), Stearyl Glycyrrhetinate (skin-soothing), Hexylene Glycol (hydration), Caprylyl Glycol (preservative), Ethylhexylglycerin (preservatives), Phenoxyethanol (preservative).

Ratings & Reviews

Happily Surprised


I love this Serum! When I first recieved it as a sample, I thought, "I can't use that, it'll irritate my skin." But I kept it. After doing some research on smoothing scars, I came upon information about retinol's effectiveness and remembered the sample was still in the drawer. I've used retinol products before for acne (years ago--that was before discovering PC) and they made my skin red and blotchy. Decided to try it and my skin looked great the next day. Soft, smooth, and radiant. No irritation whatsoever. I'll definitely be purchasing this product.




Wouldn't be without


This is a fantastic retinol serum. A little goes a long way. Soaks right in and not greasy. I tried the 1% retinol and had a terrible reaction. However the 1% I can use on my hands and that has done wonders. This serum goes great w/my regimen as well. I use it am/pm. Try it you won't want to be w/out.

Nahnee of 2

Oshkosh WI


Love this Serum


My skin feels silky smooth within minutes of application, just wait a few minutes and it's all absorbed into my skin, and the wrinkles are less pronounced. I like how bright my skin looks after using it. I find it easy to apply, and just a few little dabs are enough to do my whole face and decollete. Couldn't get through the winter in the cold northeast without this serum. Seems to be fragrance free, which is a big plus for me. Highly recommended from this sensitive skinned freckled redhead over age 55!


Northern New York state


Like liquid silk


This serum is HG status for me. I use it every single night except for when i use my DE Babyfacial, and my skin looks so much better than it ever has in my LIFE. It's silky smooth, and just sinks right in, and plays nicely with the rest of my regimen. I will be using this until I die!


Lafayette, LA


Smooths skin


I love the way my face feels in the morning after applying this serum the night before, so smooth, refined, and moisturized. It spreads so well and a little goes a long way.


Los angeles

Best product out there


I love this product! I use it twice a day and my skins looks so much better when I have in on.


Dubuque, IA


The only retinol for me


This product is gentle on my skin, and little goes a long way. It's the only retinol based product that hasn't irritated my skin to the point where I get discouraged and give up. I love this product and my skin loves it because I've never looked better. I definitely recommend this product, and I never want to be without it!


Miami, FL


Would hate to be without this product


I've been using this since 2013 and wouldn't want to know what my skin would look like without this, lol. I don't do or get Botox, fillers or any professional skin treatments and truly believe that PC products have kept my skin looking amazing through the years. This retinol serum works wonders on my skin and I'd hate to be without it. It doesn't irritate my skin like the 1% clinical retinol did when I tried it. Maybe as I get older, I'll try that again, but for now this is just perfect for me.




I have used this since June 2016. Love it!


I ran out once about a year ago and thought I would just use Neutrogena Advanced Wrinkle Repair. That lasted about two weeks. My skin was not as smooth or moisturized. The tiny lines were much more visible and even started to appear on my cheeks. Not happy. Reordered this Resist serum and within a week those lines I was seeing on my cheeks were gone. I cleanse with Cetaphil, less expensive and cleans well without drying, followed with PC Skin Perfecting BHA 2% then this serum. Even at (gulp!) almost 50 I was still getting pimples and black heads. My skin not only looked better it cleared up. I still get an occasional hormonal flare but I now feel comfortable enough to go out with just a good sunscreen and some mascara. Another benefit! I would never before have left the house without make up! People comment now that I do not look my age! I look at friends I have known since childhood and can see a major difference in the amount of aging on their faces and mine. Can't recommend this enough! I only wish I had this in my 20's!


Central Texas

This is my favorite serum ever!


This is the best serum ever! You will definitely can feel difference.



RESIST Intensive Wrinkle-Repair Retinol Serum

4.1 567