RESIST Super Antioxidant Serum
Based on 425 reviews
A hydrating, antioxidant-enriched serum that restores visible radiance for dull, dry skin while fighting against environmental attack.

RESIST Super Antioxidant Serum

Based on 425 reviews
A hydrating, antioxidant-enriched serum that restores visible radiance for dull, dry skin while fighting against environmental attack.
  • Essential for improving visible signs of aging
  • Improves the appearance of dull, uneven skin tone
  • Restores hydration to dry, sun damaged skin
  • Use twice daily after cleansing, toning, and exfoliating
Skin Types:
Dry Skin
Wrinkles, Anti-Aging
    1 oz
    Travel Size...
Why is it different?

RESIST Super Antioxidant Concentrate Serum contains an impressive range of plant- and vitamin-derived antioxidants that work synergistically to visibly improve the appearance of wrinkles, uneven skin tone, dryness, and vibrancy.

What does it do?
Stabilized Vitamin C and peptides plus potent antioxidants combine to help preserve and rejuvenate skin’s surface and to visibly enhance firmness. This state-of-the-art serum helps minimize damage from environmental attack that cause skin to look older, while also helping to visibly improve a dull skin tone for smooth, radiant results.
How to use

Smooth a few drops onto face, neck and eye area before moisturizing. For optimal results, use AM and PM. For daytime, follow with a broad-spectrum sunscreen rated SPF 30 or greater.

Show details
Research Evidence Based Complementary Alternative Medicine, 2013, volume 2013, article 827248

Phytotherapy Research, February 2014, issue 2, pages 159-66

American Journal of Clinical Dermatology, 2003, issue 2, pages 107-29

Life Sciences, October 2014, issue 1, pages 1-7

Journal of Drugs in Dermatology, September 2014, issue 9, pages 1021-5

Journal of Cosmetic Dermatology, September 2007, issue 3 pages 183-8

Journal of Investigative Dermatology, October 2005, issue 4, pages 826-32

International Journal of Cosmetic Science, February 2000, issue 1, pages 21-52

Journal of Drugs in Dermatology, September 2014, issue 9, pages 1021-5

Indian Dermatology Online Journal, April-June 2013, issue 2, pages 143-146

Plastic Surgical Nursing, April-June 2012, issue 2, pages 71-2

International Journal of Cosmetic Science, April 2000, issue 2, pages 85-94

Indian Dermatology Online Journal, April-June 2013, issue 2, pages 143-146

Dermatologic Therapy, September-October 2007, issue 5, pages 314-21

Biofactors, 1999, issue 2-4, pages 371-8

Product Ingredients

Cyclopentasiloxane, Dimethicone (hydrations/suspending agents), Tetrahexyldecyl Ascorbate (vitamin c/antioxidant), Palmitoyl Tripeptide-5 (skin-restoring ingredient), Ceramide NP, Tocotrienols, Tocopherol (vitamin e/antioxidant), Ubiquinone (coenzyme q10/antioxidant), Thioctic Acid (alpha lipoic acid/antioxidant), Tocopheryl Acetate (vitamin e/antioxidant), Magnesium Ascorbyl Phosphate ( vitamin c/antioxidant), Ferulic Acid (antioxidant), Beta-Glucan (skin-soothing), Superoxide Dismutase (antioxidant), Epigallocatechin Gallate (antioxidant), Ergothioneine (antioxidant), Glutathione (antioxidant), Xanthophylls (antioxidant), Glycine Soja Seed Extract (soybean extract/antioxidant), Glycerin (hydration/skin replenishing), Arctostaphylos Uva Ursi Leaf Extract (bearberry extract/skin-soothing), Lupinus Albus Seed Extract (white lupin extract/antioxidant), Curcuma Longa Root Extract (turmeric extract/antioxidant), Elaeis Guineensis Oil (palm oil/emollient), Phenoxyethanol (preservative).

Ratings & Reviews

Perfect for dry sensitive skin


I've been using this for years, it is wonderful for night time. Doesn't cause any irritation (so many do) but actually soothes my skin. I use it after I wash my face and before I put my more irritating skin care on like retinol. It's an essential part of my skin care that helps reduce irritation and moisturize.




Five stars


This serum is perfect for me. It has kind of a thick texture for a serum so it's perfect for dry skin. I have dry sensitive reddened skin from rosacea that typically will not tolerate vitamin C but I have finally found my HG vit C product. Thank you Paula!! Over the last 10yrs I have been trying to find a vitamin C serum my face will tolerate and was about to completely call it quits when I took a chance and ordered this. I've tried so many different C products from the cheap to extremely expensive medical grade products with no luck. I use this twice a day with zero irritation and highly recommend this especially if you thought you couldn't tolerate vitamin C.




WONDERFUL Powerhouse Serum!!!


I am 53 years' old, have ULTRA sensitive skin with rosacea, and have tried many, many (too many) products to combat dryness, sensitivity, and rosacea all at the same time. This serum is absolutely without doubt the best skin care treatment I've ever used. Highly recommend it. There are a couple of Paula's Choice products that I wouldn't buy again because I did have a reaction, but this isn't one of them. I cannot rave about it enough.


Oakville, ON


Wonderful serum - rosacea / sensitive skin


I've been using this serum for well over a year. Started at age 29 after a long fruitless search for products to help with my rosacea. My case was fairly mild but I still had a lot of redness on my cheeks, some bumps, and occasionally, a burning sensation. I've been using the Skin Recovery Moisturizer, which I also really like, for about 2 years and while it didn't irritate my rosacea, it didn't improve it either. Pretty quickly after I started using this serum, I noticed a significant difference. While it's not gone by any means, there is definitely less redness than there used to be, the bumps are smoother, and I haven't had a single episode of burning sensation the whole time I've been using this. My skin can be sensitive but it really seems to love this. I notice a big difference when I don't use it. Overall, my skin looks healthier and better than it did 2 years ago. I mostly credit this serum.


Tampa, Florida


Works Great On Oily, Sensitive Man Skin. Here's How...


I have oily, super-sensitive skin and can't use the Ultra-Light Super Antioxidant Concentrate Serum as it contains Niacinamide. My skin won't tolerate it. This product doesn't contain it and works great. As PC advisors have said, this is super concentrated and you only need a few drops. I use 1 small drop on my forehead area, then use 2 small drops on my lower face (cheeks, nose, eyes), plus an additional small drop on my neck. With my oily skin, it goes on kind of thick but just give it 5-10 minutes to soak in and it's like it was never there. I'm a guy, and honestly, my sensitive skin turns slightly red when I first apply it, however it does that just from washing it. After the 5-10 minute period my skin is back to normal (with the Ultra-Light it was red all day). The best part is when I wake up in the morning, my skin is very soothed and refreshed.


Asheville, NC


Atrocious Price Increases!


Love this serum. 2011 this was $24.00. Seven years later it's $38.00. The consumer's skin is obviously not the main focus for Paula's Choice. Just about priced it out of my market, and at this price there are many other manufacturers' in this category to pick from. My solution: I use it once a day instead of twice, and I no longer buy Paula's Choice products for my relatives like I used to because of the high price increases for essentially the same products in same sizes. Consequently, Paula's Choice makes less money from me and has less product exposure to others than in the past.

Golden Oldie





Scent free! Easily absorbed! Use everywhere! Just does a great job of keeping skin well-hydrated, smooth, and younger looking. I use this on the vertical lines around my mouth, and the creases there also. I apply it in those areas in the morning before my foundation. It can be used around the eyes also, but I've taken to using Paula's RESIST anti-aging eye cream, another great product which also serves as a good eye shadow base. Since the serum is so easily absorbed and scent-free, I'll using it on my neck and chest also - scentless, so can layer perfume over. Along with the anti-aging eye cream, this serum is an important part of my base layer every morning before make-up.


St. Louis, Missouri




Love this. I add this to the intensive repair cream, as it is a thicker serum. My skin has never felt more hydrated!! Such a great quality serum. A must need for skin.




My daily staple!


I've been using PC products for about 5 years and my skin at 46 thanks me! I absolutely love this serum from the Resist line and use it in both my morning and evening routines. I always mix it with a little PC Vit C boost and together both go on beautifully and smooth. In the morning before I put on my foundation, it dries nicely and leaves no sticky residue. I can't live without this stuff (I used to use Olay Regenerist serum instead which is fab too but they test on animals). Thank you PC for another wonderful product!


Cayman Islands


Rich serum!


I love, love, love this serum! It's true that it is thick but can be used for different things. In the summer I use this as my night moisturizer when I don't want anything heavy. It can be used as an under eye moisturizer for day, under an SPF product. I'm now 56 & have been using it since I was in my 30's. Recently I started my own business & didn't have the budget for it until you offered a special, thank you, Paula!


Battle Creek, MI



4.1 425